Green synthesis and biomedicinal applications of silver and gold nanoparticles functionalized with methanolic extract of
            <i>Mentha longifolia</i>

Rauf, Abdur; Ahmad, Touqeer; Khan, Ajmal; Maryam,; Uddin, Ghias; Ahmad, Bashir; Mabkhot, Yahia N.; Bawazeer, Sami; Riaz, Nadia; Malikovna, Bates Kudaibergenova; Almarhoon, Zainab M.; Al‐Harrasi, Ahmed

doi:10.1080/21691401.2021.1890099

Cited by 47 publications

(22 citation statements)

References 57 publications

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“…Some properties, such as concentration, size, surface charge, and shape, are very important to the antimicrobial effects of AuNPs. In aqueous medium, NPs interact with negatively charged microorganisms to return to their positively charged form, with the effect of electrostatic attraction [ 44 , 45 ].…”

Section: Resultsmentioning

confidence: 99%

The Investigation of the Chemical Composition and Applicability of Gold Nanoparticles Synthesized with Amygdalus communis (Almond) Leaf Aqueous Extract as Antimicrobial and Anticancer Agents

et al. 2023

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The current work’s main objective was to determine the chemical composition of Amygdalus communis (AC) leaf extract and examine the antibacterial and cytotoxic properties of biosynthesized gold nanoparticles (AuNPs). The chemical composition of AC leaf extract was determined using LC-ESI/MS/MS to detect compounds that may be responsible for the reducing, stabilizing, and capping steps in the synthesis of nanoparticles and their biological activities. The AC-AuNPs were spherical, with a particle size lower than 100 nm and a face-centered cubic structure. The EDX spectrum confirmed the formation of AuNPs and a negative zeta potential value (−27.7 mV) suggested their physicochemical stability. The in vitro cytotoxic efficacy of the AC-AuNPs against colorectal adenocarcinoma (Caco-2), glioma (U118), and ovarian (Skov-3) cancer cell lines and human dermal fibroblasts (HDFs) was evaluated by MTT assay. CaCo-2 cell proliferation was effectively inhibited by the AC-AuNPs at concentrations between 25 and 100 g mL−1. The AC-AuNPs exerted preeminent antimicrobial activity against Bacillus subtilis with an MIC of 0.02 μg/mL, whilst good activity was shown against Staphylococcus aureus bacteria and Candida albicans yeast with an MIC of 0.12 μg/mL. Ultimately, the results support the high antibacterial and anticancer potential of biosynthesized AuNPs from AC leaf extract.

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Section: Resultsmentioning

confidence: 99%

The Investigation of the Chemical Composition and Applicability of Gold Nanoparticles Synthesized with Amygdalus communis (Almond) Leaf Aqueous Extract as Antimicrobial and Anticancer Agents

et al. 2023

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“…The round oval morphology of silver nanoparticles with a mean size of 10.23 ± 2 nm was revealed by TEM. Mentha longifoliabased silver nanoparticles showed tremendous antibacterial effect toward S. aureus (ZOI = 12 ± 0.03 mm), B. subtilis (ZOI = 10 ± 0.01 mm), and K. pneumonia (ZOI = 0) and antioxidant activities [192]. In another research, the biological fabrication of silver nanoparticles was explained by Ocimum Americanum, with a particle size of 48.25 nm.…”

Section: Synthesis Of Silver Nanoparticles Using Leaf Extracts: (2019-2020)mentioning

confidence: 97%

Green Synthesis of Metal and Metal Oxide Nanoparticles Using Different Plants’ Parts for Antimicrobial Activity and Anticancer Activity: A Review Article

et al. 2021

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Nanotechnology emerged as a scientific innovation in the 21st century. Metallic nanoparticles (metal or metal oxide nanoparticles) have attained remarkable popularity due to their interesting biological, physical, chemical, magnetic, and optical properties. Metal-based nanoparticles can be prepared by utilizing different biological, physical, and chemical methods. The biological method is preferred as it provides a green, simple, facile, ecofriendly, rapid, and cost-effective route for the green synthesis of nanoparticles. Plants have complex phytochemical constituents such as carbohydrates, amino acids, phenolics, flavonoids, terpenoids, and proteins, which can behave as reducing and stabilizing agents. However, the mechanism of green synthesis by using plants is still highly debatable. In this report, we summarized basic principles or mechanisms of green synthesis especially for metal or metal oxide (i.e., ZnO, Au, Ag, and TiO2, Fe, Fe2O3, Cu, CuO, Co) nanoparticles. Finally, we explored the medical applications of plant-based nanoparticles in terms of antibacterial, antifungal, and anticancer activity.

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“…In addition, the biosynthesis of AuNPs and AgNPs using the Mentha longifolia extract produces nanoparticles that are able to inhibit cyclooxygenase enzymes (COX-1, COX-2) so that they have painkilling properties as well. These studies proved that AuNPs and AgNPs synthesized using plant extracts are potential alternative agents to treat inflammation [ 73 ].…”

Section: Synthesis Of Gold and Silver Nanoparticles Using Plant Extractsmentioning

confidence: 99%

Biosynthesis of Gold and Silver Nanoparticles Using Phytochemical Compounds

2023

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Gold and silver nanoparticles are nanoparticles that have been widely used in various fields and have shown good benefits. The method of nanoparticle biosynthesis utilizing plant extracts, also known as green synthesis, has become a promising method considering the advantages it has compared to other synthesis methods. This review aims to give an overview of the phytochemical compounds in plants used in the synthesis of gold and silver nanoparticles, the nanoparticle properties produced using plant extracts based on the concentration and structure of phytochemical compounds, and their applications. Phytochemical compounds play an important role as reducing agents and stabilizers in the stages of the synthesis of nanoparticles. Polyphenol compounds, reducing sugars, and proteins are the main phytochemical compounds that are responsible for the synthesis of gold and silver nanoparticles. The concentration of phytochemical compounds affects the physical properties, stability, and activity of nanoparticles. This is important to know to be able to overcome limitations in controlling the physical properties of the nanoparticles produced. Based on structure, the phytochemical compounds that have ortho-substituted hydroxyl result in a smaller size and well-defined shape, which can lead to greater activity and stability. Furthermore, the optimal condition of the biosynthesis process is required to gain a successful reaction that includes setting the metal ion concentration, temperature, reaction time, and pH.

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Green synthesis and biomedicinal applications of silver and gold nanoparticles functionalized with methanolic extract of Mentha longifolia

Cited by 47 publications

References 57 publications

The Investigation of the Chemical Composition and Applicability of Gold Nanoparticles Synthesized with Amygdalus communis (Almond) Leaf Aqueous Extract as Antimicrobial and Anticancer Agents

The Investigation of the Chemical Composition and Applicability of Gold Nanoparticles Synthesized with Amygdalus communis (Almond) Leaf Aqueous Extract as Antimicrobial and Anticancer Agents

Green Synthesis of Metal and Metal Oxide Nanoparticles Using Different Plants’ Parts for Antimicrobial Activity and Anticancer Activity: A Review Article

Biosynthesis of Gold and Silver Nanoparticles Using Phytochemical Compounds

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