Green synthesis and characterization of zinc oxide nanoparticle using insulin plant ( Costus pictus D. Don ) and investigation of its antimicrobial as well as anticancer activities

Abstract

In this work we aim to synthesize biocompatible ZnO nanoparticles from the zinc nitrate via green process using leaf extracts of the Costus pictus D. Don medicinal plant. FTIR studies confirm the presence of biomolecules and metal oxides. X-ray diffraction (XRD) structural analysis reveals the formation of pure hexagonal phase structures of ZnO nanoparticles. The surface morphologies of ZnO nanoparticles observed under a scanning electron microscope (SEM) suggest that most ZnO crystallites are hexagonal. EDX analysis confirms the presence of primarily zinc and oxygen. TEM images show that biosynthesized zinc oxide nanoparticles are hexagonal and spherical. The plausible formation mechanisms of zinc oxide nanoparticles are also predicted. The biosynthesized zinc oxide nanoparticles exhibit strong antimicrobial behavior against bacterial and fungal species when employing the agar diffusion method. Synthesized ZnO nanoparticles exhibit anticancer activity against Daltons lymphoma ascites (DLA) cells as well as antimicrobial activity against some bacterial and fungal strains.

Green Synthesis of ZnO Nanoparticles using Jasminum Fluminense Leaf Extract and its Spectral and Optical Characterization Studies

“…These images depicts that the nanoparticles are hexagonal, rod shaped and some of them are spherical at different magnifications. These spherical structures indicate the presence of amorphous nature of ZnO nanoparticles [2]. The average diameter of the ZnO nanoparticle is found to be 20 nm which is correlated with the earlier reports [18].…”

“…Metal nanoparticles can be prepared by both physical and chemical methods such as UV irradiation, microwave irradiation, chemical reduction, photochemical method, electron irradiation and sonoelectrochemical method [1]. But these s are costly, labor intensive and hazardous to environment as well as living organisms and in order to eliminate this we need an alternative, environmentally friendly, cost-effective and safest approach [2]. So green approach of nanoparticle gained great attention among scientists and literature review divulges that leaves are generally used for the synthesis of metal nanoparticles because they act as both reducing and stabilizing 2 ], Sodium hydroxide [NaOH] pellet and glasswares were purchased from Merck and used as received and Jasminum Fluminense leaves were collected from SDNB Vaishnav College Campus.…”

“…But these s are costly, labor intensive and hazardous to environment as well as living organisms and in order to eliminate this we need an alternative, environmentally friendly, cost-effective and safest approach [2]. So green approach of nanoparticle gained great attention among scientists and literature review divulges that leaves are generally used for the synthesis of metal nanoparticles because they act as both reducing and stabilizing 2 ], Sodium hydroxide [NaOH] pellet and glasswares were purchased from Merck and used as received and Jasminum Fluminense leaves were collected from SDNB Vaishnav College Campus. The leaves and all the glasswares were thoroughly washed with double distilled water before use.…”

New frontiers in the biosynthesis of metal oxide nanoparticles and their environmental applications: an overview

“…The O-H stretch appears in the spectrum as a very broad band extending at 3372.37 cm −1 . This very broad O-H stretch band is observed with a C=O peak, which almost certainly indicates that the compound is an aliphatic carboxylic acid [147]. FTIR spectrum of Jacaranda mimosifolia flowers (JMFs) extract synthesized ZnONPs exhibits a broad peak at 3373.12 cm −1 corresponding to O-H stretching vibration whereas the peaks at 2942.29 cm −1 , 2830.04 cm −1 , 1647.43 cm −1 and 1031.62 cm −1 correspond to C-H stretching, carbonyl group (C=O) and C-H bending, respectively.…”

Sintesis Nanopartikel Codoped Ceria Melalui Metode Sol-Gel Menggunakan Ekstrak Jeruk Lemon (Citrus limon) Sebagai Agen Pengkelat

“…Hasil pengamatan morfologi menggunakan SEM ditunjukkan pada Gambar 3. Berdasarkan Gambar 3, beberapa nanopartikel yang dihasilkan mengalami aglomerasi sehingga ukuran partikel tampak besar yaitu melebihi 100 nm, hal ini serupa dengan laporan Suresh et al (2018). Namun demikian, berdasarkan puncak difraksi sinar X yang lebar dan didukung dengan perhitungan Scherrer maka partikel yang dihasilkan dapat dikategorikan nanopartikel.…”