Green Synthesis and Characterization of Highly Stable Silver Nanoparticles from Ethanolic Extracts of Fruits of Annona muricata

Gavamukulya, Yahaya; Maina, Esther N.; Meroka, Amos M.; Madivoli, Edwin Shigwenya; El‐Shemy, Hany A.; Wamunyokoli, Fred; Magoma, Gabriel

doi:10.1007/s10904-019-01262-5

Cited by 53 publications

(34 citation statements)

References 39 publications

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“…Similarly, the strong relationship between AgNPs absorption spectra at extreme acidic and alkaline pH conditions of 2 and 11 could be attributed to these conditions have nearly similar effects on the AgNPs. This behavior is in line with earlier studies that showed that extreme changes in pH affect the shape and size of the particles because of the pH's ability to alter the charge of biomolecules by having the potential to affect their capping as well as stabilizing abilities leading to a shift in the peak wavelength thereby indicating a slight increase in size of the particles [47,54,55]. Generally, the reported stability plays a critical role in ensuring maintenance of effectiveness of the AgNPs and thus helps overcome one of the obstacles encountered by many conventional crude extracts from plants which lose effectiveness in vivo due to the changing pH gradients as previously reported [38].…”

Section: Resultssupporting

confidence: 92%

“…The AgNPs size was on average smaller as presented by DLS (68.7 nm) as compared to XRD (87.36 nm), but higher than that as calculated by TEM (55 nm). This difference could be explained by the fact that the size measured by DLS is based on a combination of the particles as well as the hydrodynamic radius which is not a true size of the AgNPs due to the hydration layer around the particles as well as the presence of capping and stabilizing agents as previously explained [47,53,57]. Finally, PDI measures the homogeneous nature of nanoparticles, whereby the smaller the PDI the more homogeneous nanoparticles.…”

Section: Resultsmentioning

confidence: 99%

“…The hydrodynamic size distributions and polydispersity index (PDI) of the silver nanoparticles were analyzed by using dynamic light scattering (DLS) instrumentation. The average particle size, size distribution by intensity as well as PDI were determined by injecting 1:20 dilution of silver nanoparticle resuspension into the U-shaped glass cuvette of the photon correlation microscope as previously reported [47,50,53,57]. The spectrum shown in Fig.…”

Section: Dynamic Light Scattering (Dls)mentioning

confidence: 99%

“…Silver nanoparticles (AgNPs) are of particular interest because of their antimicrobial, anticancer and cytotoxic activities. We previously reported about the successful synthesis of silver nanoparticles from ethanolic extracts of fruits of Annona muricata [47], nevertheless, there had been no reported method or publication on the use of ethanolic extracts of Annona muricata to prepare nanoparticles from leaves of this plant, despite their known therapeutic potential. The aim of this study was therefore to optimize a method for the synthesis of AgNPs from ethanolic extracts of leaves of Annona muricata as well as to characterise the green synthesised AgNPs.…”

Section: Introductionmentioning

confidence: 99%

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Synthesis and Characterization of Silver Nanoparticles from Ethanolic Extracts of Leaves of Annona muricata: A Green Nanobiotechnology Approach

Gavamukulya¹,

Maina

Wamunyokoli

et al. 2019

BJI

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Introduction: The biological green synthesis of nanoparticles via nanobiotechnology processes have a significant potential to boost nanoparticles production without the use of harsh, toxic, and expensive chemicals commonly used in conventional physical and chemical processes. Annona muricata, a tropical plant belonging to family Annonaceae is one of the most used plants in folk medicine because of its many medicinal uses and therefore presents a strong candidate for use in green synthesis. Aims: The aim of this study was to optimize a method for the synthesis of Silver Nanoparticles (AgNPs) from ethanolic extracts of leaves of Annona muricata as well as to characterize the green synthesized AgNPs. Methodology: AgNPs were synthesized from Annona muricata leaves using AgNO3 solution. The AgNPs were characterized using spectroscopy and microscopy techniques. Results: The formed AgNPs had an absorption maximum at 429 nm using UV–Visible spectroscopy and were stable under different pH, temperature, and storage conditions. Fourier transform infrared analysis revealed the different functional groups responsible for the synthesis and stabilization of the AgNPs. Scanning electron microscopy analysis revealed a spherical nature of the synthesized AgNPs. Energy dispersive x-ray spectroscopy analysis showed presence of Ag, O, and Cl with Ag having the highest composition at 60%. X-Ray Diffraction and Dynamic Light Scattering revealed a crystalline nature of AgNPs with an average size of 87.36 nm and a polydispersity index of 0.16 respectively. Transmission Electron Microscopy analysis further confirmed the crystalline and spherical nature of the AgNPs. Conclusion: In this article, an efficient, eco-friendly and low-cost method for the synthesis and recovery of stable AgNPs using Annona muricata leaves ethanolic extracts as both a reducing and capping agent has been reported for the first time. The synthesized AgNPs could be promising candidates for many biomedical, clinical, engineering, and polymer applications.

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Section: Resultssupporting

confidence: 92%

Section: Resultsmentioning

confidence: 99%

Section: Dynamic Light Scattering (Dls)mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Synthesis and Characterization of Silver Nanoparticles from Ethanolic Extracts of Leaves of Annona muricata: A Green Nanobiotechnology Approach

Gavamukulya¹,

Maina

Wamunyokoli

et al. 2019

BJI

Self Cite

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“…Previously prepared and characterized AgNPs from ethanolic extracts of fruits and leaves of Annona muricata were used for the study from which the current data was obtained [1], [2]. AgNPs-F used had an absorption maximum at 427 nm and were stable under different pH, Temperature and storage conditions.…”

Section: Experimental Design Materials and Methodsmentioning

confidence: 99%

In search of new anticancer drugs: Data for cytotoxic activities of green synthesized silver nanoparticles from ethanolic extracts of fruits and leaves of Annona muricata and 5-Fluorouracil against HeLa, PC3 and PNT1A cell lines

et al. 2019

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In this article, we present data on the anticancer activities of green synthesized silver nanoparticles (AgNPs) from ethanolic extracts of fruits (AgNPs-F) and leaves (AgNPs-L) of Annona muricata and standard anticancer drug 5-Fluorouracil (5-FU) on two cancer cell lines, i.e. cervical adenocarcinoma (HeLa cells) and prostate adenocarcinoma (PC3 cells) as well as on an immortalized normal prostate cell line, PNT1A. The cytotoxicity on the cells was determined by measuring the absorbance signal of resazurin dye. It has long been known that metabolically active cells change the resazurin from blue (oxidized) to red (reduced) forms, corresponding to the absorbance signals at a wavelength of 570nm (A570) and 600nm (A600) respectively, from which therefore the effects of any treatments on percentage cell viability/death can be elucidated. The raw data values of the treatments against the HeLa, PC3 and PNT1A cells are shown in the different Tables. Examples of how the data can be analyzed have been illustrated using different growth inhibition curves. The data can be used by academics, students, and researchers working on development of anticancer drugs.

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Plant‐Mediated Green Synthesis of Magnetic Spinel Ferrite Nanoparticles: A Sustainable Trend in Nanotechnology

Wani

Suresh

2022

Advanced Sustainable Systems

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Nanotechnology is very important in developing sustainable technologies for the future. Increased demand for metal and metal oxide nanoparticles has led to their large‐scale production using conventional chemical methods with various toxic solvents. These techniques produce poisonous and harsh products that present a biological risk to the environment and have terrible effects on the life of microbes, plants, vertebrates, and invertebrates at different trophic levels. Thus eco‐friendly “green” synthesis methods have become necessary to synthesize nanoparticles using biological entities, such as plants and microorganisms. When compared to other methods, “green” synthesis is safer for human health and the environment. Plants, the main factory for the green synthesis of nanoparticles, have been used extensively for this purpose. This review, focuses on eco‐friendly synthesis to design spinel ferrite nanoparticles, particularly, using extracts from plant products that act not only as precursors but also as reductants and stabilizers during the synthesis process. The outstanding features of these nanoparticles allows for their promising applications in catalysis, lithium‐ion batteries, information storage, magnetic cores, ferrofluids, microwave, and medicine. This important review also highlights noteworthy recent developments related to the green synthesis of plant‐mediated magnetic spinel nanoparticles and their fundamental applications.

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Green Synthesis and Characterization of Highly Stable Silver Nanoparticles from Ethanolic Extracts of Fruits of Annona muricata

Cited by 53 publications

References 39 publications

Synthesis and Characterization of Silver Nanoparticles from Ethanolic Extracts of Leaves of Annona muricata: A Green Nanobiotechnology Approach

Synthesis and Characterization of Silver Nanoparticles from Ethanolic Extracts of Leaves of Annona muricata: A Green Nanobiotechnology Approach

In search of new anticancer drugs: Data for cytotoxic activities of green synthesized silver nanoparticles from ethanolic extracts of fruits and leaves of Annona muricata and 5-Fluorouracil against HeLa, PC3 and PNT1A cell lines

Plant‐Mediated Green Synthesis of Magnetic Spinel Ferrite Nanoparticles: A Sustainable Trend in Nanotechnology

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