Green Synthesis, Characterization, and Antifungal Activity of Synthesized Silver Nanoparticles (AgNPS) from Garcinia Kola Pulp Extract

Abstract

The prevention or cure of microbial infections are mostly combated with the use of antibiotics. However, the activity of most of the available antibiotics had been nullified by fungi resistance. This study was aimed at the investigation of the antifungal property of silver nanoparticles (AgNPs) synthesized from Garcinia kola pulp. The pulp of Garcinia kola were obtained from its ripe fruit, dried and pulverized into fine particles and extracted with water. The extract was mixed with 1mM aqueous silver nitrate following necessary procedure to form AgNPs. The AgNPs synthesized were characterized and screened against tested fungi using standard method. The inhibition zones were measured and recorded after incubation of the plates at a temperature of 35 °C for 24 h. The morphological assessment of the synthesized AgNPs confirmed the variation in particle size ranging from 24 to 10 nm with an average size distribution of 17 nm and a spherical shape. The synthesized AgNPs show good activity against tested fungi strains with inhibition zones ranging from 6 to 17 mm which is comparable to the inhibition zones demonstrated by the control in the range of 18 to 24 mm. This study indorsed the use of AgNPs against fungi infections owning to the antifungal activity displayed against tested fungi strains. Keywords Silver nanoparticles • Garcinia kola pulp • Clinical isolates and fungi activity

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Phytonano silver for cosmetic formulation- synthesis, characterization, and assessment of antimicrobial and antityrosinase potential

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