“…Carbon quantum dots (CQDs) are uorescent semiconductor nanoparticles that have recently been used in pharmaceutical and biomedical analysis by measuring the enhancement or quenching of the uorescent signal from the CQDs as a result of an interaction of the CQDs with the compound of interest. [45][46][47][48][49][50] Originally, CQDs were prepared from primary chemical precursors such as citric acid, polyethyleneimine, zinc oxide, phenolic resins, and ethylene glycol, which were incompatible with concepts of green analytical chemistry. [51][52][53][54] Therefore, scientists have recently focused on nding environmentally friendly precursors from nature as substitutes, such as biomass wastes and plant-derived pharmaceuticals, because they are environmentally friendly, widely available, biocompatible, and rich in low-cost renewable raw materials (rich in C, H, N, and O atoms) such as polysaccharides, proteins, nucleic acids, and phospholipids.…”