Green synthesis of gold and silver nanoparticles using aqueous extract of Cibotium barometz root

Abstract

Green synthesis of gold (CB-AuNps) and silver (CB-AgNps) nanoparticles using Cibotium barometz root extract was highlighted. CB-AuNps were synthesized almost instantly and CB-AgNps were formed after 25 min in a heated aqueous extract. The formation of CB-AuNps and CB-AgNps was detected at 548 and 412 nm; they were spherical with crystallite sizes of 6 nm and 23 nm, respectively. CB-AgNps were further investigated for their antimicrobial activity against Escherichia, Staphylococcus aureus, Salmonella enterica, and Pseudomonas aeruginosa. Furthermore, scavenging activity against 1,1-diphenyl-2-picrylhydrzyl (DPPH) free radicals was demonstrated. Lastly, the cytotoxic properties of CB-AuNps and CB-AgNps were explored in murine macrophages (RAW264.7) cells and MCF-7 breast cancer cells. This study demonstrated the prospective biomedical applications of CB-AuNps and CB-AgNps as antioxidant, antimicrobial agents, and drug-delivery agents.

Potential anticancer activity of biogenic silver nanoparticles using leaf extract of Rhynchosia suaveolens: an insight into the mechanism

“…The formation of the RS-AgNPs was started at 3 h and completed at 24 h. The peak was found to stable at 12, 18 and 24 h at the same wavelength of 426 nm. The absorption peak is due to the excitation of SPR which is characteristic of RS-AgNPs and consistent with earlier reports [26][27][28]. To the best of our knowledge, this was the first report on the biosynthesis of RS-AgNPs using leaf extract of R. suaveolens.…”

“…The biological synthesis of RS-AgNPs using aqueous leaf extracts of R. suaveolens was evident by a variation in the color from colorless to brownish-yellow of oxidized silver nitrate solution in dark condition. Color change was an initial indication for the formation of RS-AgNPs [10,[26][27][28]. Further the confirmation of the biosynthesis of RS-AgNPs was done by UV-Vis analysis.…”

“…Biosynthesized AgNPs from Clerodendrum phlomidis exhibited potent cytotoxicity against HT29 human colorectal adenocarcinoma (HT29) and Ehrlich ascites carcinoma(EAC) cells [52]. Biosynthesized AgNPs from Cibotium barometz and Chaenomeles sinensis showed anticancer activity against MCF-7 cells [27,28]. AgNPs synthesized with leaf extract of Sesbania grandiflora showed potent cytotoxicity against MCF-7 cells [53].…”

“…Hence, the biological methods for the synthesis of AgNPs have become prime choice. The biological or biosynthesis methods of AgNPs including bacterial assisted [23], fungal mediated [24], actinomycetes mediated [25] and plant assisted methods [26][27][28] have been reported as simple, rapid, inexpensive and ecofriendly approaches which are alternative to physical and chemical methods. Different plant extracts including Anthemis atropatana [29], Bauhinia variegata [30], Caesalpinia pulcherrima [31], Cassia fistula [32], Euphrasia officinalis [33], Glycyrrhiza uralensis [34], Indigofera tinctoria [35], Ipomoea batatas [36], Prosopis juliflora [37] and Punica granatum [38] have been successfully reported for the biosynthesis of AgNPs.…”

“…The demand for AgNPs has increased due to their vast applications in biomedicine, pharmacy, agriculture and food industry which leads to the development of clean, nontoxic and biocompatible AgNPs. Plant synthesized AgNPs are being successfully employed not only as anti-bacterial, antifungal [26][27][28], anti-viral [39], anti-inflammatory [40], wound healing [41], anti-angiogenic treatment [42] cancer diagnosis and drug delivery but also in bio imaging [9][10][11]43]. Further, plant synthesized AgNPs are biocompatible and nonhemolytic [10,13].…”