Green synthesis of silver nanoparticles using Solanum indicum L. and their antibacterial, splenocyte cytotoxic potentials

Abstract

Green synthesis of silver nanoparticles was carried out using Solanum indicum L. plant extract as a reducing agent. The morphology of the AgNPs was determined by transmission electron microscopy. Scanning electron microscopy and energy-dispersive spectroscopy (EDX) were used to characterize the nanoparticles obtained from S. indicum L. The EDX analysis of the nanoparticles dispersion, using a range of 2-4 keV, confirmed the presence of elemental silver, without any contamination. The green synthesized AgNPs were evaluated against the pathogens such as Staphylococcus sp., (Accession No. KC688883) and Klebsiella sp., (Accession No. KC899845). The AgNPs (1-4 mM) extensively inhibit the growth of the pathogens. Cytotoxic potential of the synthesized AgNPs was analyzed against rat splenocytes. The percentage of viable cells was diminished according to the increasing concentration of AgNPs.

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