Green tea: A promising natural product in oral health

Narotzki, Baruch; Reznick, Abraham Z.; Aizenbud, Dror; Levy, Yishai

doi:10.1016/j.archoralbio.2011.11.017

Cited by 129 publications

(114 citation statements)

References 37 publications

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“…Bioactive natural metabolites derived from various plant extracts have shown potential oral benefits (Shinada et al, 2007;Macedo et al, 2009;Bedran-Russo et al, 2011;Pavan et al, 2011;Narotzki et al, 2012). To the best of our knowledge, this is the first study to systematically evaluate the dentin bioactivity of different and well-defined sources of PACs and correlate these findings with their phytoconstituent profiles.…”

Section: Discussionmentioning

confidence: 99%

Dentin Biomodification Potential Depends on Polyphenol Source

et al. 2014

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Although proanthocyanidins (PACs) modify dentin, the effectiveness of different PAC sources and the correlation with their specific chemical composition are still unknown. This study describes the chemical profiling of natural PAC-rich extracts from 7 plants using ultra high pressure/performance liquid chromatography (UHPLC) to determine the overall composition of these extracts and, in parallel, comprehensively evaluate their effect on dentin properties. The total polyphenol content of the extracts was determined (as gallic acid equivalents) using FolinCiocalteau assays. Dentin biomodification was assessed by the modulus of elasticity, mass change, and resistance to enzymatic biodegradation. Extracts with a high polyphenol and PAC content from Vitis vinifera, Theobroma cacao, Camellia sinensis, and Pinus massoniana induced a significant increase in modulus of elasticity and mass. The UHPLC analysis showed the presence of multiple types of polyphenols, ranging from simple phenolic acids to oligomeric PACs and highly condensed tannins. Protective effect against enzymatic degradation was observed for all experimental groups; however, statistically significant differences were observed between plant extracts. The findings provide clear evidence that the dentin bioactivities of PACs are source dependent, resulting from a combination of concentration and specific chemical constitution of the complex PAC mixtures. A supplemental appendix to this article is published electronically only at http://jdr.sagepub.com/supplemental.

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Section: Discussionmentioning

confidence: 99%

Dentin Biomodification Potential Depends on Polyphenol Source

et al. 2014

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“…Yet, another publication demonstrates on a large number of volunteers that green tea does not alter liver functions in any way [158]. The most recent publications have examined the biochemical and pharmaceutical properties of tea catechins and their impact on human health [159][160][161][162][163][164]. We would like to conclude this review with an appeal, 'Drink tea for the benefits to your health!'…”

Section: Resultsmentioning

confidence: 99%

Beneficial Effect of Tea on Human Health

Yashin¹,

Yashin²,

Nemzer³

2013

Am. J. Biomed. Sci.

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Tea, with its 5,000-year history, is one of the most popular beverages in the world. According to various estimates, over 4 billion people consume tea. This number has increased in recent years due to the widespread marketing of cold tea-based beverages. During the first millennium tea was primarily considered to be medicine rather than an ordinary drink. Over the last few years a large number of epidemiological studies have conclusively proven that tea is beneficial for people with cardiovascular and neurodegenerative diseases, and cancers. Tea catechins are included in numerous dietary supplements and medicinal products. This review summarizes scientific information related to the effects of tea on human health which have been published in the last decade.

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“…Besides polyphenols, GTE contains additional antioxidants such as carotenoids, tocopherols (vitamin E derivatives) and vitamin C. Tea contains also minerals that function as co-factors in antioxidant enzymes: zinc, selenium and manganese. Polyphenols have additional mechanisms in which they reduce oxidation level besides direct role as antioxidants [32,33]. The antifibrotic effect of GTE explained by some authors who reported that it might be through the inhibition exerted by GTE on gelatinases involved in the damage to lung extracellular matrix, matrix metalloproteinases [18] and others have demonstrated that GTE both inhibits the signal transduction of TGF-β by binding to transforming growth factor receptor II (TGFR) and attenuates the expression of α-smooth muscle actin (α-SMA) in MRC-5 cells (human lung fibroblasts), which is a myofibroblast cell line, when it is stimulated by TGF-β.…”

Section: Discussionmentioning

confidence: 99%

Modulatory effects of green tea and aloe vera extracts on experimentally-induced lung fibrosis in rats: histological and immunohistochemical study

Salem¹,

El-Azab²,

Faruk³

2014

J Histol Histopathol

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Background: Pulmonary fibrosis (PF) is a multifactorial disease in the human. The existing therapeutic agents display unfavorable adverse effects. Consequently, the discovery of novel therapeutic agents for the prevention and treatment of PF remains a challenge. Aim of the work: Evaluation of the modulatory effect of green tea and aloe vera (AV) extracts on bleomycin induced pulmonary fibrosis in rats. Material and methods: Fifty adult male rats were utilized and divided equally into 5 groups. The first was served as control group, the second was the bleomycin (BLM) group (daily I.P. dose 10 mg/kg body weight for 10 days), the third was the green tea (GTE) group which was given daily oral dose of GTE (150 mg/ kg b.w.) for 14 days with concomitant IP administration of BLM for 10 consecutive days, the fourth was the Aloe vera (AV) group which was given daily oral dose of AV (300 mg/kg b.w.) for 14 days with concomitant IP administration of BLM for 10 consecutive days, the fifth was the GTE and AV group. Lung samples were taken 14 days after the treatment. Paraffin sections were prepared for histological; H&E and Masson's trichrome staining and immunohistochemical study. Results: Green tea group revealed normal bronchioles, alveoli with apparently thin interalveolar septa, few cellular infiltration and extravasated RBCs and induced a significant decreased (P≤0.05) in collagen fibers accumulation and in caspase-3 expression compared with BLM group. Group IV (AV) and group V (GTE and AV) revealed alveoli with apparently thicker interalveolar septa, more cellular infiltration, congested blood vessels and extravasated RBCs in comparison with GTE group. Group IV showed insignificant decreased (P≤0.05) in collagen fibers accumulation compared with BLM group while the decrease was significant in caspase-3 expression. Group V showed insignificant decreased (P≤0.05) in collagen fibers accumulation and in caspase-3 expression compared with BLM group. Conclusion: Green tea and aloe vera partially alleviate pulmonary fibrosis induced by bleomycin in rats. Supporting the potential benefits of using aloe vera and green tea as a potential novel therapeutic agents by diet.

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Green tea: A promising natural product in oral health

Cited by 129 publications

References 37 publications

Dentin Biomodification Potential Depends on Polyphenol Source

Dentin Biomodification Potential Depends on Polyphenol Source

Beneficial Effect of Tea on Human Health

Modulatory effects of green tea and aloe vera extracts on experimentally-induced lung fibrosis in rats: histological and immunohistochemical study

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