Green tea (Camellia sinensis) for the prevention of cancer

Boehm, Katja; Horneber, Markus; Borrelli, Francesca; Ernst, Edzard

doi:10.1002/14651858.cd005004

Cited by 74 publications

(89 citation statements)

References 24 publications

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“…These studies demonstrated that green tea and its major constituents such as catechins might inhibit tumorigenesis at a number of organ sites, involving stomach, prostate, liver, colon, bladder, esophagus and lung [33]. However, in contrast to accumulating evidence from animal models, a Cochrane review published conflicting results regarding the cancerpreventive effects of green tea consumption in humans [34][35][36]. More recent studies also provided heterogeneous findings [23,26,38].…”

Section: Introductionmentioning

confidence: 99%

Association of green tea consumption with mortality from all-cause, cardiovascular disease and cancer in a Chinese cohort of 165,000 adult men

Liu

Zhou

et al. 2016

Eur J Epidemiol

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Tea is the most ancient and popular beverage in the world, and its beneficial health effects has attracted tremendous attention worldwide. However, the prospective evidence relating green tea consumption to total and cause-specific mortality is still limited and inconclusive. We recruited 164,681 male participants free of pre-existing disease during 1990-1991, with green tea consumption and other covariates assessed by the standardized questionnaire and mortality follow up continued until 2006 (mean 11 years; total person-years: 1,961,791). Cox regression analyses were used to quantify the associations of green tea consumption with all-cause (n = 32,700), CVD (n = 11,839) and cancer (n = 7002) mortality, adjusting simultaneously for potential confounders. At baseline, 18 % reported regular consumption of green tea. Compared with non-green tea drinkers, regular drinkers had significantly lower all-cause mortality, with adjusted hazard ratios (HRs) being 0.94 (95 % CI 0.89, 0.99) for ≤5 g/day, 0.95 (0.91, 0.99) for 5-10 g/day and 0.89 (0.85, 0.93) for >10 g/day. For CVD mortality, the corresponding HRs were 0.93 (0.85, 1.01) 0.91 (0.85, 0.98) and 0.86 (0.79, 0.93), respectively, while for cancer they were 0.86 (0.78, 0.98), 0.92 (0.83, 1.00) and 0.79 (0.71, 0.88), respectively. The patterns of these associations varied by smoking, alcohol drinking and locality. This large prospective study shows that regular green tea consumption is associated with significantly reduced risk of death from all-cause, CVD and cancer among Chinese adults.

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Section: Introductionmentioning

confidence: 99%

Association of green tea consumption with mortality from all-cause, cardiovascular disease and cancer in a Chinese cohort of 165,000 adult men

Liu

Zhou

et al. 2016

Eur J Epidemiol

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“…Ainsi, dans la revue générale des publications montrant l'efficacité des extraits de gui en cancérologie, Ernst et al [11] mettent en évidence les faiblesses de ces études en matière de méthode et de résultat. De même, la méthodologie des études épidé-miologiques concernant la préven-tion du cancer par le thé vert s'est avérée très discutable [7].…”

Section: Discussionunclassified

La fraude en cancérologie

Schraub

Ayed

2010

Oncologie

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“…A Cochrane review in 2009 on green tea included 27 case-control studies, 23 cohort studies and one randomised control trial (RCT) [131]. The RCT found that a preparation of green tea catechins reduced the risk of progression of high grade prostate intra-epithelial neoplasia to prostate cancer (p < 0.01) [132].…”

Section: Teamentioning

confidence: 99%

“…The RCT found that a preparation of green tea catechins reduced the risk of progression of high grade prostate intra-epithelial neoplasia to prostate cancer (p < 0.01) [132]. However, attempts to draw conclusions based on reviewing data from cohort and case control studies of tea consumption have been inconclusive [131,133].…”

Section: Teamentioning

confidence: 99%