Computational fluid dynamics is employed to predict the aerodynamic properties of the prototypical trailing-edge control surfaces for a small, regional transport, commercial aircraft. The virtual experiments are performed at operational flight conditions, by resolving the mean turbulent flow field around a realistic model of the whole aircraft. The Reynolds-averaged Navier–Stokes approach is used, where the governing equations are solved with a finite volume-based numerical method. The effectiveness of the flight control system, during a hypothetical conceptual pre-design phase, is studied by conducting simulations at different angles of deflection, and examining the variation of the aerodynamic loading coefficients. The proposed computational modeling approach is verified to have good practical potential, also compared with reference industrial data provided by the Leonardo Aircraft Company.