“…At last, ''osteointegration'' describes the surface bonding between the host bone and the grafting material (Constantino & Freidman, 1994). The most desirable form of bone substitute is the autologous bone graft for their superior osteoconduction, ease of incorporation, lack of immunological reactions, contains living bone cells that offer osteogenesis and growth factors that stimulate osteoinduction (Cypher & Grossman, 1996;Naber et al, 1972;Marciani et al, 1977). However, massive replacements of bone are not easily achieved by bone autografts as autogenous bone is limited in availability, and may result in the donar site morbidity (Mankin et al, 1976).…”