Gross Morphological Variation in Preterm Placenta in Gestational Diabetes Mellitus and Pregnancy Induced Hypertension

Akhter, Fahima; Ferdousi, R; Sultana, Rayhana

doi:10.3329/jemc.v1i2.11466

Cited by 6 publications

(12 citation statements)

References 15 publications

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“…In the present study it was found to be more significant than Boyd et al [22] findings of which was 23% more in GDM than the normal. Also the numbers of cotyledons were increased in GDM [23] in the present study.…”

Section: Control (N=48) Range (Mini-maxi) Gdm (N=48) Range (Mini-maxisupporting

confidence: 64%

Gross Morphological Study of Gestational Diabetes Mellitus Placenta From South Indian Mothers Compared With Control Placenta

P¹,

K²,

Kiran³

et al. 2017

IJAR

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Section: Control (N=48) Range (Mini-maxi) Gdm (N=48) Range (Mini-maxisupporting

confidence: 64%

Gross Morphological Study of Gestational Diabetes Mellitus Placenta From South Indian Mothers Compared With Control Placenta

P¹,

K²,

Kiran³

et al. 2017

IJAR

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“…In the present study, the gross anatomic features of placental weight, thickness and diameter were significantly greater in GDM (p<0.0001) as compared to normal and coincides with earlier studies. 23,24 Weight of the babies was found to be significantly high when compared to the normal cases which can be attributed to one of the impact of the hyperglycaemia in GDM conditions. In the present study, the same has been revealed with the foetoplacental index which was calculated from weight of the baby/weight of the placenta and was found to be significant (p<0.02).…”

Section: Discussionmentioning

confidence: 94%

Morphological and Micrometrical Changes of the Placental Terminal Villi in Normal and Pregnancies Complicated With Gestational Diabetes Mellitus

P¹,

K²,

M³

et al. 2016

jebmh

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Incidence of gestational diabetes mellitus (GDM) is escalating in Indian women amounting to 10% of the total pregnancies mainly due to the diet, obesity and sedentary life style. Placenta is a crucial organ of intrauterine life. The functional units of the placenta such as chorionic villi, foetal blood vessels, and the syncytial knots are altered histologically in gestational diabetic condition. The present study is undertaken to observe the morphological and micrometrical changes of the GDM and normal placenta. MATERIAL AND METHODS Total number of 96 placentas, out of which 48 are GDM and 48 from control were procured for the present study. The placentas were collected from our General Hospital, Nellore, AP. Morphology and micrometry of the placentas were studied. RESULTS The shape of placenta was similar in both groups, but the weight in GDM (537.27±131.97 g), diameter (168.2±13.23 mm) and thickness (29.9±3.45 mm) were significantly (P<0.005) increased when compared to control. The mean number (9.01±2.25 mm 3) and diameter (0.08±0.03 mm) of the terminal villi and number of foetal blood vessels (21.76±8.52 mm 3) were found to be increased in GDM, but the diameter of the blood vessel (0.04±0.02 mm) was decreased and highly significant (P<0.001). The syncytial knots and fibrinoid necrosis were also observed in GDM when compared to the normal placenta. CONCLUSION The placentas from GDM were observed with significant morphological and histological changes as compared to controls, which may alter the perinatal outcome resulting in macrosomia, congenital malformations and intrauterine growth retardation.

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“…Then, another maximum diameter was measured at the right angle to the first measured diameter and the mean of two measurements was taken as the diameter of the placenta expressed in centimeter. 20 …”

Section: Methodsmentioning

confidence: 99%

“…Placentae were weighed using a weighing machine scaled in gram and the shape and presence of accessory lobe were recorded after proper observation to be categorized as round, oval, or irregular in shape. 20 , 23 , 24 After placing each placenta on the fetal surface, with the help of a long needle, the placental thickness was measured at five different points where the placentae were arbitrarily divided into three zones by drawing two circles on the maternal side. One thickness was measured from the Center of the central zone, two from the middle zone, and another two from the peripheral zone.…”

Section: Methodsmentioning

confidence: 99%

“… 19 In addition, it can also yield information that is useful for immediate and late management of maternal and neonatal complications. 20 However, the attempt to explore its usage globally as well as in Africa has been limited due to paucity of information on the parameters of the placenta and umbilical cord, which is also sophisticated due to sociocultural belief where relatives of mother or father handle these parameters following delivery. As a result of this, using the placentae and umbilical cords for biomedical research has been significantly limited.…”

Section: Introductionmentioning

confidence: 99%

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Placental and Umbilical Cord Indices and Their Association with Fetal Distress in Hadiya Zone Public Hospitals, Southern Ethiopia: A Cross-Sectional Study

Meskele¹,

Mulu²,

Gebremickael³

et al. 2021

IJGM

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Background The placenta and umbilical cord have been considered as significant contributors to the perinatal outcome and have contributed to some degree to neonatal mortality. The placenta has a very crucial role in normal fetal development. After about four weeks of gestation, the only link of the fetus to the placenta is the umbilical cord. Very little is known about placental and umbilical indices in Ethiopia. This study was aimed to determine placental and umbilical cord indices and their association with fetal distress in Hadiya zone public hospitals, southern Ethiopia. Methods This study included 249 placentae with the attached umbilical cord from normal singleton live birth with known gestational age. Bivariable and multivariable logistic regression was used, and variables with p < 0.25 in the bivariable analysis were entered into a multivariable logistic regression to identify the independent factors for the outcome variable. Odds ratios with 95% confidence were computed, and statistical significance was declared at p-value <0.05. Results Three-fourth (75.9%) of diameter of studied placenta was in normal range and 18.1%, 6.0% below and above normal range, respectively. About one-third (32.9%) of umbilical cords were short, 61.8% normal, and 5.2% long. Newborns with thin placenta [AOR = 3.43; 95% CI: 1.25, 9.40], short cord length [AOR = 3.43; 95% CI: 1.66, 7.09] and long cord length [AOR = 7.55; 95% CI: 2.07, 27.53] were significantly associated with fetal distress. Conclusion In this study, deviation of umbilical cord length from the normal range and placental thickness were significantly associated with fetal distress. In addition, fetal distress was also associated with gestation age and sex of the newborn.

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Gross Morphological Variation in Preterm Placenta in Gestational Diabetes Mellitus and Pregnancy Induced Hypertension

Cited by 6 publications

References 15 publications

Gross Morphological Study of Gestational Diabetes Mellitus Placenta From South Indian Mothers Compared With Control Placenta

Gross Morphological Study of Gestational Diabetes Mellitus Placenta From South Indian Mothers Compared With Control Placenta

Morphological and Micrometrical Changes of the Placental Terminal Villi in Normal and Pregnancies Complicated With Gestational Diabetes Mellitus

Placental and Umbilical Cord Indices and Their Association with Fetal Distress in Hadiya Zone Public Hospitals, Southern Ethiopia: A Cross-Sectional Study

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