2010
DOI: 10.1200/jco.2010.28.15_suppl.e13159
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Group sequential design: Selecting appropriate bounds.

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Cited by 4 publications
(5 citation statements)
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“…Correspondingly, we used the gsDesign function from the gsDesign package (Anderson, 2014) with the default settings to compute the expected sample sizes for a GS design with 4 looks (3 interim tests + final test) and the matching FPE and FNE rates. Figure 4 systematically applies this comparison between the (expected) sample sizes of all three designs to all conditions of the simulation and shows the relative efficiency gain of the SBF sample size compared with the NHST-PA fixed- n benchmark and the typical GS design.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Correspondingly, we used the gsDesign function from the gsDesign package (Anderson, 2014) with the default settings to compute the expected sample sizes for a GS design with 4 looks (3 interim tests + final test) and the matching FPE and FNE rates. Figure 4 systematically applies this comparison between the (expected) sample sizes of all three designs to all conditions of the simulation and shows the relative efficiency gain of the SBF sample size compared with the NHST-PA fixed- n benchmark and the typical GS design.…”
Section: Resultsmentioning
confidence: 99%
“…We employed a GS design with four looks (three interim looks plus the final look), with a total Type I error rate of 5% and a statistical power of 95%. Necessary sample sizes and critical boundaries were computed using the default settings of the gsDesign package (Anderson, 2014). The planned sample sizes were n = 16, 31, 46, and 61 in each group for the first to the fourth look, with corresponding critical two-sided p values of .0016, .0048, .0147, and .0440.…”
Section: Three Research Designsmentioning
confidence: 99%
“…In a second step, we simulated a GS with four looks (three interim analyses and one final test) for the same population scenarios and nominal error rates. Sample sizes for each step and the respective critical values were calculated with the gsDesign package in R (K. Anderson, 2014).…”
Section: Statistical Error Rates Of Sprt Gs and Sbfsmentioning
confidence: 99%
“…We had preregistered a sequential analysis (Lakens, 2014). That is, we used the R package gsDesign (Anderson, 2016; Version 3.0–1) to determine three equally spaced time points at which we would peak at the data. At the first and second peak, the preregistered criteria for finishing the study earlier were not fulfilled.…”
Section: Methodsmentioning
confidence: 99%