Growth rate of vestibular schwannoma

Paldor, Iddo; Chen, Annie S.; Kaye, Andrew H.

doi:10.1016/j.jocn.2016.05.003

Cited by 126 publications

(99 citation statements)

References 42 publications

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“…29,33 Although not consistent across all studies, some have found tinnitus at presentation may be a predictor of poorer overall outcomes, with one study finding an increase of 2.9 (confidence interval [CI]: 1.1-7.6) in the odds ratio (OR) of tumor growth. 34,35 As a result, unilateral tinnitus in the absence of a bona fide history or event should always be evaluated with an inner ear protocol MRI (magnetic resonance imaging) to rule out inner ear or retrocochlear pathology to include but not be limited to a vestibular schwannoma.…”

Section: Epidemiology and Clinical Presentationmentioning

confidence: 99%

“…33 No baseline parameters have been found to be predictive of growth; however, growth in the 1st year is predictive of future growth. 28,35 One half to two-thirds have not grown at 5-year follow-up. 28,35 Based on data for all diagnosed VS in Denmark since 1976, if the tumor had not grown after 5 years, it did not grow.…”

Section: Treatmentmentioning

confidence: 99%

“…28,35 One half to two-thirds have not grown at 5-year follow-up. 28,35 Based on data for all diagnosed VS in Denmark since 1976, if the tumor had not grown after 5 years, it did not grow. 36 Of the patients that had American Academy of Otolaryngology (AAO) class A hearing (good and preserved hearing, pure tone average less than 30 dB and speech discrimination > 70%), 26% had lost it after 1 year, 45% after 5 years, and 54% after 10 years.…”

Section: Treatmentmentioning

confidence: 99%

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Tinnitus Management in Lateral Skull Base Lesions

San-Juan

Basura

2018

J Neurol Surg B

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Tinnitus, the phantom perception of sound in the absence of a physical sound source, is a complex problem with multiple etiologies. While most commonly presenting in a subjective fashion caused by measurable hearing loss, other etiologies including lateral skull base tumors that encroach on middle and inner ear structures can lead to phantom sound perception as well. In addition to discussing the basic background of tinnitus, here we also review current theories of etiology that include central auditory and nonauditory neural mechanisms and potential treatments that range from sound therapy to medications to cognitive and behavioral therapies and cranial nerve and brain stimulation. One main purpose of this article is to relate tinnitus causes to skull base tumors, surgical removal, and resultant sequelae, including damage to cranial nerves resulting in audiovestibular dysfunction. We also discuss the utility of microvascular decompression for both tumor and nontumor-associated tinnitus and the current literature regarding hearing preservation rates and tinnitus perception, where documented, with the three common treatment modalities employed for most lateral skull base tumors that includes watchful waiting with serial imaging, stereotactic radiosurgery and primary surgical resection using hearing preservation and hearing ablative approaches. The management of skull base tumors is a complex process that depending upon the approach and sequelae, may lead to manageable or worsening phantom sound perception that must be considered when discussing the multiple treatment options with patients.

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Section: Epidemiology and Clinical Presentationmentioning

confidence: 99%

Section: Treatmentmentioning

confidence: 99%

Section: Treatmentmentioning

confidence: 99%

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Tinnitus Management in Lateral Skull Base Lesions

San-Juan

Basura

2018

J Neurol Surg B

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“…Although most schwannomas have an indolent growth pattern, some tumors exhibit periods of more rapid growth that correlates with symptom progression. No specific factors have been found to influence schwannoma growth rate, although an association between rapid growth and cyst or hemorrhage development has been reported in vestibular schwannoma …”

Section: Introductionmentioning

confidence: 99%

Vagal schwannomas of the head and neck: A comprehensive review and a novel approach to preserving vocal cord innervation and function

et al. 2019

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Background: Schwannomas, benign tumors arising from neurolemmocytes, are the most common type of peripheral nerve tumors. Extracranial schwannomas are most often found in the parapharyngeal space, commonly involving the vagus nerve to cervical sympathetic trunk. Vagal schwannomas present several unique clinical and therapeutic challenges. Methods: A comprehensive literature review was conducted on 197 articles reporting 235 cases of cervical vagal schwannomas. Presenting symptoms, treatment approach, and postoperative outcomes were recorded and analyzed. Results: Vagal schwannomas commonly present as asymptomatic neck masses. When they become symptomatic, surgical resection is the standard of care. Gross total resection is associated with higher postoperative morbidity compared to subtotal resection. Initial reports using intraoperative nerve monitoring have shown improved nerve preservation. Recurrence rates are low. Conclusion: The combination of intermittent nerve mapping with novel continuous vagal nerve monitoring techniques may reduce postoperative morbidity and could represent the future standard of care for vagal schwannoma treatment. K E Y W O R D S continuous intraoperative nerve monitoring, nerve sheath tumor, neurilemmoma, vagal schwannoma, vagus nerve

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“…Вступ. Акустичні невриноми беруть початок з нейролемоцитів (шванівських клітин) мієлінової оболонки ПЗН або його гілок, з так званої зони Оберштейнера-Редліха, розташованої на рівні або медіальніше ВСХ [1][2][3][4]. Часто (більш ніж у 55% спостережень) пухлини досягають значних розмірів, тому визначити зону росту пухлини неможливо [5,6].…”

Section: Introductionunclassified