Growth zone segmentation in the milkweed bug <i>Oncopeltus fasciatus</i> sheds light on the evolution of insect segmentation

Auman, Tzach; Chipman, Ariel D.

doi:10.1101/327106

Cited by 7 publications

(11 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In Drosophila, opa is required for late network activation and genome-wide regulatory changes (Clark & Akam, 2016;Koromila et al, 2019;Soluri et al, 2019). In other insects, opa is expressed in a band at the end of the segment addition zone, where a putative late network would be active, though Oncopeltus lack this pattern, implying this timer gene role may not be conserved across all insects (Green & Akam, 2013;Xiang et al, 2017;Janssen et al, 2011;Auman & Chipman, 2018). Together, this correlative evidence implies that the timer genes cad, D, and opa are plausibly involved in regulating segmentation across many arthropod species.…”

Section: Introductionmentioning

confidence: 99%

Nasoniasegmentation is regulated by an ancestral insect segmentation regulatory network also present in flies

Dearden

2021

Preprint

View full text Add to dashboard Cite

Insect segmentation is a well-studied and tractable system with which to investigate the genetic regulation of development. Though insects segment their germband using a variety of methods, modelling work implies that a single gene regulatory network can underpin the two main types of insect segmentation. This means limited genetic changes are required to explain significant differences in segmentation mode between different insects. Evidence for this idea is limited to Drosophila melanogaster, Tribolium castaneum, and the spider Parasteatoda tepidariorum, and the nature of the gene regulatory network (GRN) underlying this model has not been tested. Some insects, for example Nasonia vitripennis and Apis mellifera segment progressively, a pattern not examined in studies of this segmentation model, producing stripes at different times throughout the embryo, but not from a segment addition zone. Here we aim to understand the GRNs patterning Nasonia using a simulation-based approach. We found that an existing model of Drosophila segmentation (Clark 2017) can be used to recapitulate Nasonia's progressive segmentation, if provided with altered inputs in the form of expression of the timer genes Nv-caudal and Nv-odd paired. We also predict limited topological changes to the pair rule network. Together this implies that very limited changes to the Drosophila network are required to simulate Nasonia segmentation, despite the differences in segmentation modes, implying that Nasonia use a very similar version of an ancestral GRN also used by Drosophila.

show abstract

Section: Introductionmentioning

confidence: 99%

Nasoniasegmentation is regulated by an ancestral insect segmentation regulatory network also present in flies

Dearden

2021

Preprint

View full text Add to dashboard Cite

show abstract

“…Intermediate-germ insects (e.g. the flour beetle Tribolium castaneum, the milkweed bug Oncopeltus fasciatus (36,37), and the beetle Dermestes maculatus (38)) lie somewhere in between, where anterior fates form in the blastoderm and posterior fates form in the germband stage (Figure 2A). Short-germ embryogenesis is thought to be the ancestral mode of insect development, and an evolutionary trend of short-germ to long-germ evolution is observed to occur independently several time throughout evolution (with some reports of the opposite path (39)).…”

Section: Introductionmentioning

confidence: 99%

Speeding up anterior-posterior patterning of insects by differential initialization of the gap gene cascade

Rudolf

Zellner

El-Sherif

2020

Developmental Biology

View full text Add to dashboard Cite

Recently, it was shown that anterior-posterior patterning genes in the red flour beetle Tribolium castaneum are expressed sequentially in waves. However, in the fruit fly Drosophila melanogaster, an insect with a derived mode of embryogenesis compared to Tribolium, anterior-posterior patterning genes quickly and simultaneously arise as mature gene expression domains that, afterwards, undergo slight posterior-to-anterior shifts. This raises the question of how a fast and simultaneous mode of patterning, like that of Drosophila, could have evolved from a rather slow sequential mode of patterning, like that of Tribolium. In this paper, we elucidate a mechanism for this evolutionary transition based on a switch from a uniform to a gradient-mediated initialization of the gap gene cascade by maternal Hb. The model is supported by computational analyses and experiments..

show abstract

“…The hemipteran insects that have been examined seem to employ a particularly divergent method of segmentation. Most strikingly, the pair-rule genes, generally considered the most conserved portion of the segmentation pathway among insects, have lost their pair-rule expression and function and are expressed segmentally in at least some hemipterans [7–9].…”

Section: Introductionmentioning

confidence: 99%

Segmentation pathway genes in the Asian citrus psyllid,Diaphorina citri

Miller

Shippy

Hosmani

et al. 2020

Preprint

View full text Add to dashboard Cite

Insects have a segmented body plan that is established during embryogenesis when the anterior-posterior (A-P) axis is divided into repeated units by a cascade of gene expression. The cascade is initiated by protein gradients created by translation of maternally provided mRNAs, localized at the anterior and posterior poles of the embryo. Particular combinations of these proteins activate specific gap genes to divide the embryo into distinct regions along the A-P axis. Gap genes then activate pair-rule genes, which are usually expressed in part of every other segment. The pair-rule genes, in turn, activate expression of segment polarity genes in a portion of each segment. The segmentation genes are generally conserved among insects, although there is considerable variation in how they are deployed. We annotated 24 segmentation gene homologs in the Asian citrus psyllid, Diaphorina citri. We identified most of the genes that were expected to be present based on known phylogenetic distribution. Two exceptions were eagle and invected, which are present in at least some hemipterans, but were not identified in D. citri. Many of these genes are likely to be essential for D. citri development and thus may be useful targets for pest control methods.

show abstract

Growth zone segmentation in the milkweed bug Oncopeltus fasciatus sheds light on the evolution of insect segmentation

Cited by 7 publications

References 41 publications

Nasoniasegmentation is regulated by an ancestral insect segmentation regulatory network also present in flies

Nasoniasegmentation is regulated by an ancestral insect segmentation regulatory network also present in flies

Speeding up anterior-posterior patterning of insects by differential initialization of the gap gene cascade

Segmentation pathway genes in the Asian citrus psyllid,Diaphorina citri

Contact Info

Product

Resources

About