The increasingly mechanical requirements of offshore structures have established the relevance of fracture mechanics-based quality control in welded joints. For this purpose, crack tip opening displacement (CTOD) at a given distance from the crack tip has been considered one of the most suited parameters for modeling and control of crack growth, and it is broadly used at the industrial level. We have modeled, through multivariate analysis techniques, the relationships among CTOD values and other material properties (such as hardness, chemical composition, toughness, and microstructural morphology) in high-thickness offshore steel welded joints. In order to create this model, hundreds of tests were done on 72 real samples, which were welded with a wide range of real industrial parameters. The obtained results were processed and evaluated with different multivariate techniques, and we established the significance of all the chosen explanatory variables and the good predictive capability of the CTOD tests within the limits of the experimental variation. By establishing the use of this model, significant savings can be achieved in the manufacturing of wind generators, as CTOD tests are more expensive and complex than the proposed alternatives. Additionally, this model allows for some technical conclusions.