Guidelines for pre‐transfusion compatibility procedures in blood transfusion laboratories

Forman, K.; Kelsey, P R; Murphy, Michael; Wood, J. K.; Chapman, J. F.; Baglin, Trevor; Knowles, Sue; Milkins, Clare; Poole, Geoff

doi:10.1111/j.1365-3148.1996.tb00079.x

Cited by 90 publications

(32 citation statements)

References 13 publications

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“…ANZSBT Guidelines also recommend providing RBCs that match for Rh and K types to chronically transfused patients where readily available 20 . Moreover, the United Kingdom even considered the need to recommend phenotype as fully as possible before transfusion and to match for Rh and K antigens before the onset of alloimmunization due to the excessive high risk of alloimmunization in sickle cell anemia patients 9,21 …”

Section: Discussionmentioning

confidence: 99%

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Clinically significant red blood cell antibodies in chronically transfused patients: a survey of Chinese thalassemia major patients and literature review

Cheng¹,

Lee²,

Lin³

2012

Transfusion

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It is the first comprehensive study on Chinese thalassemia major patients. Clinically significant alloantibodies are different from those observed in the Western population, although antibodies developed against Rh antigens are still common. Chinese patients are less likely to have antibodies against Kell and Duffy blood group antigens, but are more prone to develop antibodies against the Miltenberger antigens.

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Section: Discussionmentioning

confidence: 99%

“…In Hong Kong, all patients would have their pretransfusion compatibility tests at the hospital blood bank. They followed either UK standards 9 or AABB standards 10 . Pretransfusion testing included ABO group, D type, antibody screen, and compatibility testing.…”

Section: Methodsmentioning

confidence: 99%

Clinically significant red blood cell antibodies in chronically transfused patients: a survey of Chinese thalassemia major patients and literature review

Cheng¹,

Lee²,

Lin³

2012

Transfusion

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“…Panels of reagent RBCs for identification of antibodies to RBCs are typed for a list of antigens defined by government bodies 28,29 . Whereas some European regulatory agencies require D, C, E, c, e, Fy a , Jk a , and S antigens in double dose, there is no requirement of the Food and Drug Administration in the United States to be present in double dose, 30 although the AABB technical manual indicates that it is valuable to include RBC samples with a double dose of the same antigens 31 .…”

Section: Discussionmentioning

confidence: 99%

Blood group genotyping by high‐throughput DNA analysis applied to 356 reagent red blood cell samples

et al. 2010

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“…The choices are based on the principle that the recipient plasma must not contain the antibodies corresponding to donor A and/or B antigens [11,12]. Ideally, the same blood group RBC which is compatible with the recipient plasma should be transfused.…”

Section: Choice Of Blood Groupmentioning

confidence: 99%

Transfusion of Blood and Components in Critically Ill Children

2010

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The physicians prescribing transfusions must have a thorough understanding of the various blood products, their indications and contraindications, and requirements for modification of the blood products to prevent probable adverse effects. Decision to give an RBC transfusion should not be based solely on Hb concentration, it should take in account high severity of illness; active bleeding; emergency surgery; etc. Using restrictive transfusion strategy of transfusion RBCs can decrease transfusion requirements without increasing adverse outcomes. In most circumstances, platelets should be maintained greater than 10×10(9)/L. Platelet counts greater than 20×10(9)/L are indicated for invasive procedures and greater than 50×10(9)/L for major surgeries or invasive procedures with risk of bleeding. Whenever possible, ABO-compatible platelets should be administered. Fresh frozen plasma should be transfused in multiple coagulation factor deficiencies, DIC with bleeding, replacement of rare single congenital factor deficiencies when specific concentrates are not available (e.g., protein C or factor II, V, X, XI, or XIII deficiency). During transfusion child should be monitored carefully.

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Guidelines for pre‐transfusion compatibility procedures in blood transfusion laboratories

Cited by 90 publications

References 13 publications

Clinically significant red blood cell antibodies in chronically transfused patients: a survey of Chinese thalassemia major patients and literature review

Clinically significant red blood cell antibodies in chronically transfused patients: a survey of Chinese thalassemia major patients and literature review

Blood group genotyping by high‐throughput DNA analysis applied to 356 reagent red blood cell samples

Transfusion of Blood and Components in Critically Ill Children

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