Guillain-Barr� syndrome in immunocompromised patients: A report of three patients and review of the literature

Treatment of Guillain-Barré Syndrome Induced by Cyclosporine in a Lung Transplant Patient

“…A review of the literature of solid organ transplant recipients who were diagnosed with GBS reveals that the disease may occur days to years after transplantation and that most are associated with CMV infection. [2][3][4][5][6][7][8][9][10] Additionally, complete recovery appears to be the rule, regardless of therapy or if immunosuppression therapy is altered.…”

“…16 There have been multiple case reports of a Guillain-Barré-like syndrome in solid organ transplant patients that were mostly thought to be due to both the immunosuppression itself and their greater susceptibility to infection, particularly with CMV. [2][3][4][5][6][7][8][9][10] CMV infection has previously been associated with a Guillain-Barré-like syndrome, particularly in patients who have undergone transplant. A causative role of CMV in this patient appears unlikely for several reasons.…”

Increased Frequency of Guillain-Barré Syndrome in HIV Infection: A Prospective Cohort Study

“…Although most authors describe GBS as a manifestation of early HIV infection or even seroconversion, numerous reports of GBS in advanced immunosuppression are available, with CD4+ counts as low as 4 cells/mm 3 [9][10][11]. In our cohort, one third of HIV-positive patients had AIDS.…”

“…However, because this informationis derived from populations with a low prevalence of HIV infection, it does not provide information about the incidence of GBS in HIV-infected individuals. Although GBS has been reported in HIVpositive individuals [9][10][11][12] and is regarded as more frequent in this group [13], data beyond case reports and small case series is scarce. Furthermore, although the presentation and course of GBS is thought to be similar in HIV-positive and -negative an individual, no systematic investigation has been performed to explore this.…”

Muscle injury in Guillain-Barré syndrome: a case report

“…In our patient no evidence of rhabdomyolysis or human immunodeficiency virus infection as a common cause for acute myopathy and neuropathy was found [2,3,6]. The differential diagnosis of GBS also includes myopathies with electrolyte imbalance [5] (see http://www.neuro.wustl.edu/neuromuscular).…”