Guillain-Barre syndrome presenting with severe hydrocephalus in a child

Barzegar, Mohammad; Malaki, Majid

doi:10.4103/1817-1745.117868

Cited by 5 publications

(2 citation statements)

References 9 publications

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“…Although weight as a parameter is not always documented, we noticed that 5/27 patients are obese, suggesting an increased possibility of overweight and obese patients to develop ICP in GBS setting. Respiratory insufficiency and mechanical support are reported in 9/27 patients ( Table 1 ) ( 7 , 14 – 16 , 18 , 23 – 29 ).…”

Section: Discussionmentioning

confidence: 99%

“…Thus, in the current case, intracranial pressure is secondary to GBS leading to papilledema, headache, decreased vision acuity and worsen GBS symptoms with bilateral and relatively symmetric weakness of all limb muscles. In fact, papilledema with or without hydrocephalus is rarely reported in GBS ( 7 , 13 , 20 ). It appears mainly after the established limb weakness and is associated with elevated CSF protein similar to our case ( 12 ).…”

Section: Discussionmentioning

confidence: 99%

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Case Report: Intracranial Hypertension Secondary to Guillain-Barre Syndrome

et al. 2021

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Guillain-Barre Syndrome (GBS), a common cause of acute flaccid paralysis, is characterized by a rapidly progressive, usually symmetric weakness of the extremities. Headache and intracranial hypertension (ICHT) are very rare complications of GBS. Herein we report our current case of an obese girl with typical signs of GBS associated with autonomic dysfunction, cranial nerve deficits and increased intracranial pressure (ICP). We also perform a systematic study presenting and discussing previous case reports of GBS associated with ICHT, papilledema or hydrocephalus, highlighting the differences of the current case compared to previous studies. Although intracranial hypertension is a rare complication of pediatric GBS, clinicians should promptly detect it. Obesity may be a predisposing factor, given the strong association between idiopathic intracranial hypertension (IIH) and weight gain. Neurological evaluation, fundus examination and low threshold for intracranial imaging should be an integral part of medical practice in case of obesity, headache or visual changes in GBS patients.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Case Report: Intracranial Hypertension Secondary to Guillain-Barre Syndrome

et al. 2021

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Headache and Pain in Guillain-Barré Syndrome

Farmakidis

Inan

Milstein

et al. 2015

Curr Pain Headache Rep

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While moderate and severe back or extremity pain is frequent in Guillain-Barré syndrome (GBS), headache appears to be uncommon. Most of the reports of headache in GBS place it in the context of the posterior reversible encephalopathy syndrome (PRES) which is increasingly recognized as a likely dysautonomia-related GBS complication. There are also a few reports of headache in the setting of increased CSF pressure and papilledema and in association with the Miller Fisher GBS variant. In comparison, back and extremity pain is highly prevalent. Aching muscle pain and neuropathic pain are the two most common of several pain types. Pain may be a heralding feature and has been described in patients as long as 2 years after disease onset. Pain management is a major axis of treatment in GBS. Gabapentin is a reasonable first-line choice, and opioid medications can be added for more severe pain but there are few clinical trials to inform specific recommendations. While the understanding of pain pathophysiology in GBS is incomplete, its prevalence and clinical impact are increasingly recognized and studied. Pain should be considered a cardinal manifestation of GBS along with acute, mostly symmetric weakness and diminished reflexes.

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Headache and intracranial hypertension in Guillain-Barré syndrome: a case report and literature review

Wang

Guo

2019

International Journal of Neuroscience

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Guillain-Barre syndrome presenting with severe hydrocephalus in a child

Cited by 5 publications

References 9 publications

Case Report: Intracranial Hypertension Secondary to Guillain-Barre Syndrome

Case Report: Intracranial Hypertension Secondary to Guillain-Barre Syndrome

Headache and Pain in Guillain-Barré Syndrome

Headache and intracranial hypertension in Guillain-Barré syndrome: a case report and literature review

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