Gustatory evoked magnetic fields in humans

Murayama, Nobuki; Nakasato, Nobukazu; Hatanaka, Koji; Fujita, Satoshi; Igasaki, Tomohiko; Kanno, Akira; Yoshimoto, Takashi

doi:10.1016/0304-3940(96)12680-x

Cited by 34 publications

(14 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Bilateral gustatory losses following unilateral CNS lesions suggest that the branching of the ascending taste pathways into crossed and uncrossed components can occur at different levels, from the mesencephalon [20,62], to the pons [39] or the thalamus [33,62], but, contrary to rodents, in primates the ascending taste pathway from the nucleus of the solitary tract does not synapse in the parabrachial nucleus of the pons, but bypasses it to terminate in the thalamus [46,48,55]. Bilateral cerebral activation from unilateral taste stimulation of the tongue has been verified using gustatory magnetic field recording by Murayama et al [32] and confirmed with electrogustatory lingual stimulation [31,66]. Aglioti et al [1,2] and Iannilli et al [23] have presented evidence to suggest that the ipsilateral component of the afferent taste pathway is predominant over the contralateral component, while the opposite appears to be the case for the afferent tactile projections from the tongue [10,50].…”

Section: Discussionmentioning

confidence: 98%

Functional MRI cortical activations from unilateral tactile-taste stimulations of the tongue

Mascioli

Berlucchi

Pierpaoli

et al. 2015

Physiology & Behavior

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 98%

Functional MRI cortical activations from unilateral tactile-taste stimulations of the tongue

Mascioli

Berlucchi

Pierpaoli

et al. 2015

Physiology & Behavior

View full text Add to dashboard Cite

“…As for the central gustatory pathway in humans, it is known that the chorda tympani and glossopharyngeal nerves enter the ipsilateral nucleus tractus solitarius in the medulla and ascend to the pons [37], but the pathway above the midbrain remains unclear and is only inferred from physiological studies and cases with central lesions [23,[38][39][40][41]. In patients with taste disorders due to central lesions, there are many cases with ipsilateral taste disorders in which the lesional sites are located from the medulla to the pons, as described in the ''Results'' section for laterality [2-7, 10, 11].…”

Section: Central Gustatory Pathwaymentioning

confidence: 99%

Clinical study of central taste disorders and discussion of the central gustatory pathway

et al. 2011

View full text Add to dashboard Cite

The aim of this work is to examine the clinical findings of patients with taste disorders due to central lesions and also to study the central gustatory pathway in humans. We conducted a retrospective review of 13 patients with central taste disorders that visited Nihon University Itabashi Hospital. An additional 25 cases with central taste disorders previously reported in the literature were assessed in the study. We examined 38 patients with taste disorders due to central lesions. The sites of the central lesions and their frequencies, the laterality of taste disorders relative to the central lesions, and prognosis of taste disorders were studied. We identified the following taste-related regions in the central nervous system: the medulla, pons, midbrain, thalamus, internal capsule, putamen, corona radiata, and cerebral cortex. As for the laterality of the taste disorders, we observed more ipsilateral cases for lesions located from the medulla to the pons. We observed ipsilateral, contralateral, and bilateral cases for lesions located above the midbrain, but bilateral cases were more frequently detected. Taste disorders of 80% of the patients improved by 24 weeks. The prognoses of central taste disorders appeared to be good. We identified eight central regions supposed to be relate to taste disorders. From the laterality of the taste disorders relative to the central lesions, it was suggested that the central gustatory pathway ascends ipsilaterally from the medulla to the pons, branches at the upper pons, and then ascends bilaterally from the midbrain to the cerebral cortex.

show abstract

“…[6][7][8][9] Some data suggest that the insula may function as the primary gustatory cortex within humans, as it responds directly to changes in specific taste stimuli. [10][11][12] The insula is activated directly when subjects taste a salty or sweet stimulus 13,14 and shows increased activity in response to the smell of food. 15 Neuroimaging studies have also shown that the insular cortex is sensitive to appetitive status, 16 with heightened activation of the insula during hunger 17,18 and decreased activation after subjects have eaten to satiation.…”

Section: Introductionmentioning

confidence: 99%