2003
DOI: 10.1034/j.1600-0609.2003.00077.x
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Haematuria and urolithiasis in patients with haemophilia

Abstract: Recurrent haematuria was present in 18 of 474 moderate and severe haemophiliacs, the cause of which was found to be urolithiasis in six patients (33%). The prevalence of urolithiasis in haemophiliacs was found to be significantly higher than that reported from the general population, i.e. 4.5 of 10 000 population under 40 yr of age (odds ratio (OR) 23.4; 95% CI 18.2-28.7; lambda2 test P < 0.01). Even when this prevalence was corrected for gender bias, i.e. male : female (5 : 1), the significance of the present… Show more

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Cited by 16 publications
(15 citation statements)
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“…The prevalence of urolithiasis is higher in hemophilia patients as compared to controls (odds ratio 17.6) [12]. Furthermore, in this study it was documented that urolithiasis was the cause of recurrent hematuria in 33% of the cases.…”
Section: Renal Abnormalitiessupporting
confidence: 51%
“…The prevalence of urolithiasis is higher in hemophilia patients as compared to controls (odds ratio 17.6) [12]. Furthermore, in this study it was documented that urolithiasis was the cause of recurrent hematuria in 33% of the cases.…”
Section: Renal Abnormalitiessupporting
confidence: 51%
“…Van den Putte found a trend (P = 0.05), but the information is based on a single question reported by patients and the paper does not clarify whether there was a correlation between renal functioning and haematuria episodes [9]. It is known that other causes for haematuria apart from renal bleeds or renal disorders exist in the urinary tract or elsewhere [35][36][37]. Even though the effect of haematuria on hypertension is possible, it might be small and it could also be that higher blood pressure triggers more haematuria [22,26,27] or that only a part of macro-scopic haematuria episodes have their root in kidney disease or kidney bleeding.…”
Section: Discussionmentioning
confidence: 94%
“…(Level 4) [ ] Raise the patient's factor levels (refer to Tables 7‐1 and 7‐2) if there is pain or persistent gross hematuria and watch for clots and urinary obstruction. (Level 4) [ ] Do not use antifibrinolytic agents. (Level 4) [ ] Evaluation by an urologist is essential for evaluation of a local cause if hematuria (gross or microscopic) persists or if there are repeated episodes.…”
Section: Treatment Of Specific Hemorrhagesmentioning
confidence: 99%