1960
DOI: 10.1136/hrt.22.4.483
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HAeMODYNAMIC STUDIES IN HIGH OUTPUT BERI-BERI

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Cited by 78 publications
(26 citation statements)
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“…The two cases reported here correspond exactly with this description. The laboratory data in four cases in the literature [3,8,19,20] are concordant with our own: severe metabolic acidosis with an anion gap, a sharp fall in blood thiamin levels (especially in its phosphorylated form) and/or of red cell transketolase activity. Metabolic acidosis in S.B.B.…”
Section: Discussionsupporting
confidence: 88%
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“…The two cases reported here correspond exactly with this description. The laboratory data in four cases in the literature [3,8,19,20] are concordant with our own: severe metabolic acidosis with an anion gap, a sharp fall in blood thiamin levels (especially in its phosphorylated form) and/or of red cell transketolase activity. Metabolic acidosis in S.B.B.…”
Section: Discussionsupporting
confidence: 88%
“…Blacket has shown that in the traditional "congestive" beriberi (C.B.B. ), the blood flow resistance varies according to the region [8]. This means that the drop in T.P.R.…”
Section: Discussionmentioning
confidence: 97%
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“…However, most cases did not fit that hypothesis as they had low-output HF, were well nourished, and responded poorly to thiamine. Blacket and Palmer resolved the situation: 'It [beriberi] responds completely to thiamine, but merges imperceptibly into another disease, called ACM, which doesn't respond to thiamine' [6]. Beriberi is characterized by generalized peripheral arteriolar dilation with a resultant large arteriovenous shunt and high cardiac output at rest.…”
Section: Historymentioning
confidence: 99%
“…On the other hand, these alterations have consequences, such as an increase in peripheral venous pressure and renal retention of sodium and water 4 , during which edema may be established, even in the absence of clear evidence of heart failure.…”
Section: Case Reportmentioning
confidence: 99%