Haemogram Parameters in the Development of Retinopathy of Prematurity

Akdogan, Muberra; Demirag, Didem Arda; Varal, İpek Güney; Çevik, Sadık Görkem; Üstündağ, Yasemin

doi:10.4236/ojoph.2018.82011

Cited by 5 publications

(3 citation statements)

References 18 publications

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“…The most significant factors are oxidative stress caused by oxygen (O 2 ) and O 2 metabolites [1,2] and associated inflammation [3]. Studies demonstrating that Hb and Hb products, as well as haemogram parameters, are responsible for O 2 transport can be effective on ROP in infants, as they support the role of oxidative stress in ROP development [4].…”

Section: Introductionmentioning

confidence: 99%

The Thiol-Disulfide Homeostasis and Coenzyme Q10 in Conjunction with Vitamin E Effect on Retinopathy Prematurity

Akdogan¹,

Üstündağ²,

Akdag³

et al. 2019

TOOPHTJ

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Purpose: This study was performed to determine whether one drop of topical administration of Coqun® (Coenzyme Q10 and Vitamin E)-a potent antioxidant-twice a day has any effect on the thiol-disulphide homeostasis-a novel oxidative stress marker in the Retinopathy Of Prematurity (ROP) disease course. Methods: This was a prospective observational study comprising 28 infants with ROP at stage 2 and higher who followed up at the paediatric intensive care unit. Ferric reducing power of plasma (FRAP), albumin, ischemia-modified albumin (IMA) and thiol disulphide homeostasis levels were studied in the infants before and two weeks after Coqun® treatment. Results: The mean gestational age was 27 (24–32) weeks, the mean birth weight was 1,012±326 g and the mean duration of care in an incubator was 64±23 days. FRAP levels were 0.91±0.17 μmol/L, IMAs were 0.85±0.29, native thiols were 248±38.9 μmol/L and total thiols were 284±39.2 μmol/L, respectively, at the beginning of therapy. FRAP levels 0.79±0.21(p= 0.006) μmol/L, IMAs 0.73±0.36(p = 0.096), native thiols 262±42.6(p = 0.164) μmol/L and total thiols 291±43.6(p = 0.344) μmol/L showed no difference after two weeks of therapy. Conclusion: Thiol disulphide homeostasis levels do not change with Coqun® therapy during ROP course.

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Section: Introductionmentioning

confidence: 99%

The Thiol-Disulfide Homeostasis and Coenzyme Q10 in Conjunction with Vitamin E Effect on Retinopathy Prematurity

Akdogan¹,

Üstündağ²,

Akdag³

et al. 2019

TOOPHTJ

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“…In studies conducted so far, the most critical risk factor for ROP was found to be retinal vascular immaturity determined by low gestational age (GA) and low birth weight [2] [3] [4] [5]. Other risk factors include oxygen toxicity, acidosis, intraventricular hemorrhage, patent ductus arteriosus, sepsis, hyperbilirubinemia, low Apgar score, mechanical ventilation, and blood transfusion [6] [7] [8]. However, other preventable factors are still being investigated.…”

Section: Introductionmentioning

confidence: 99%

The Possible Role Serum Biochemical Analysis Can Play in Predicting an Infant’s Risk of Retinopathy of Prematurity; Elevated Serum Magnesium

Akdogan¹,

Sabaner²,

Üstündağ³

et al. 2019

JBM

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Purpose: We evaluated biochemical analysis results with the aim of discovering serum levels that have possible effects on the development of retinopathy of prematurity (ROP). Methods: A retrospective study was conducted between January 2017 and January 2018 on a total of 110 infants with 35 or less gestational weeks. The sample included 78 infants who had been diagnosed with different stages of ROP and 32 infants without ROP. Results from routine serum biochemical analyses, performed at birth and at one month after birth, were evaluated. The Independent Sample t-test and Mann-Whitney U test were performed to compare the data. Results: The infants with ROP were born at a mean of 28.0 (±2.1) weeks of gestation, weighing a mean of 1066 (±314) g, and the mean duration of stay in the incubator was 38.2 (±19) days. The infants without ROP were born at a mean of 29.6 (±2.6) weeks of gestation, weighing a mean of 1265 (±372) g. 59 infants (53.6%) were females, and 51 (46.4%) were males. Between infants with and without ROP, differences in the following levels were not statistically significant: glucose, blood urine nitrogen, creatinine, alanine aminotransferase, aspartate aminotransferase, albumin, total protein, direct bilirubin, indirect bilirubin, uric acid, and phosphorus. Serum magnesium (Mg) levels at birth in infants with ROP were significantly higher than infants without ROP (p = 0.014). Conclusions: Serum Mg levels at birth were found to be higher in infants with ROP than in those without ROP. The levels may be dependent on the mothers' treatment of Mg for different medical reasons.

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“…Most of the Hieroglyphic Luwian inscriptions found to the north of the Kızılırmak River have been known for a very long time (for KARABURUN see already Anderson 1901, for ÇALAPVERDİ 1-2 Forrer 1927 who already talks about Tabalite inscriptions, for ALİŞAR Gelb 1935: 73), the only exceptions being the KIRŞEHİR-letter, found and published not long ago (Akdoğan/Hawkins 2007-08 and) and a further fragment, that may or may not belong to this letter . However, until today, most of the publications, not only those written by non-specialists, but also Hittitologists, mark the northern border of Tabal with the river called Kızılırmak (without any argumentation).…”

Section: Introductionmentioning

confidence: 99%

Introduction

Mouton¹

2017

Hittitology Today: Studies on Hittite and Neo-Hittite Anatolia in Honor of Emmanuel Laroche’s 100th Birthday

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The parwala-men of the king gave one talent of copper (and) three animal-shaped vessels of beads (containing) one-half BÁN of beads. In addition, the parwala-men of the king gave three talents of copper, x talents of tin, two copper pipes, six copper sickles, 昀椀ve copper wakšur-vessels, and two oxshaped vessels of beads (containing) one-half BÁN of beads." iv. Hittite dataFor purposes of the present study, lexemes with collective meaning have been collected from the dictionaries and their attestations were checked in the Arbeitsstelle "Hethitische Forschungen" of the Akademie der Wissenschaften und der Literatur, Mainz. 3 As a result, 29 examples of collective subjects in the singular (Controller) followed by plural predicate verbs (Target) have been found: KUB 21.1 i 63' (hist.) KUB 46.22 i 7'f. (inv.) KUB 6.41 i 25 (hist.) KBo 2.13 obv. 10 (inv.) KBo 5.6 i 15f. (hist.) KBo 2.13 obv. 11 (inv.) KUB 1.1 i 30 (hist.) KBo 2.13 obv. 19 (inv.) KUB 19.10 i 6' (hist.) KBo 2.13 rev. 3f. (inv.) KBo 3.4 iv 36'f. (hist.) KBo 2.7 obv. 26' (inv.) KUB 11.13 v 25' (rit.) KUB 17.35 i 5' (inv.) KUB 1.14 ii 8'f. (rit.) KUB 17.35 i 33' (inv.) KUB 46.27 i 13' (rit.) KUB 17.35 ii 27'f. (inv.) KUB 39.4+ rev. 27f. (rit.) KUB 17.35 iv 13 (inv.) KUB 22.70 rev. 51f. (or.) KUB 17.35 iv 24' (inv.) KUB 22.70 rev. 54f. (or.) KUB 17.35 iv 25' (inv.) KUB 16.16 obv. 13' (or.) KUB 41.34 i 6'f. (inv.) KUB 40.95 ii 5f. (inv.) KBo 2.8 ii 2 (inv.

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Haemogram Parameters in the Development of Retinopathy of Prematurity

Cited by 5 publications

References 18 publications

The Thiol-Disulfide Homeostasis and Coenzyme Q10 in Conjunction with Vitamin E Effect on Retinopathy Prematurity

The Thiol-Disulfide Homeostasis and Coenzyme Q10 in Conjunction with Vitamin E Effect on Retinopathy Prematurity

The Possible Role Serum Biochemical Analysis Can Play in Predicting an Infant’s Risk of Retinopathy of Prematurity; Elevated Serum Magnesium

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