In this paper, a novel three-dimensional integrated spoof surface plasmon polaritons (SSPPs) transmission line (TL) is proposed. The controlled slow surface wave can propagate along unit cells that are planted on a metal strip periodically, which is similar to the typical SSPPs TLs. The dispersion characteristics and high-order modes of the proposed TL are studied. In order to verify the transmission performance of the proposed TL, a two-dimensional (2D) structure is utilized to do like the conversion. We have designed the proposed TL and give the simulated results from 10-25GHz, which show good propagation performance. The ohmic losses and dielectric losses of the proposed TL and typical 2D SSPPs TLs are simulated and compared with the microstrip line, coplanar waveguide. The measured data for the proposed TL indicates that the measured results are close to the simulations. The low-loss and highly integrated characteristics of the proposed TL plays an important role in the microwave and terahertz SSPPs transmission and integrated circuits. INDEX TERMS Spoof surface plasmon polaritons (SSPPs), dispersion characteristics, high-order modes, loss characteristics.