2013
DOI: 10.1021/cr9002215
|View full text |Cite
|
Sign up to set email alerts
|

Halogenated Organic Molecules of Rhodomelaceae Origin: Chemistry and Biology

Abstract: Comprehensive tables (Tables S1−S16) containing detailed information for each halomolecule including compound name (synonyms, if applicable), molecular formula, halogenation/ structural features, source species, sample collection locality, and references. This information is available free of charge via the Internet at http://pubs.acs.org/.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

2
156
0
3

Year Published

2013
2013
2024
2024

Publication Types

Select...
6
2

Relationship

2
6

Authors

Journals

citations
Cited by 205 publications
(161 citation statements)
references
References 517 publications
2
156
0
3
Order By: Relevance
“…ED 50 (10 −3 μM) Teuscher et al 2006;Wang et al 2013). However, most of the metabolites were produced under axenic or dixenic cultures, which also precluded the utilization and transformation of host metabolites (Koshimura et al 2009).…”
Section: Metabolic Relevancementioning
confidence: 97%
See 1 more Smart Citation
“…ED 50 (10 −3 μM) Teuscher et al 2006;Wang et al 2013). However, most of the metabolites were produced under axenic or dixenic cultures, which also precluded the utilization and transformation of host metabolites (Koshimura et al 2009).…”
Section: Metabolic Relevancementioning
confidence: 97%
“…Among them, the halogenated (chlorinated and/or brominated) metabolites account for 6.0 %, lower than the proportions in red algae, green algae, and sediment-derived microbes and higher than those in brown algae, mangrove-, sponge-, and coral-derived microbes as well as the whole investigated organisms (Cabrita et al 2010;Gribble 2010;Wang et al 2013;Zhao et al 2013;Ji and Wang 2014). On the other hand, the sulfur-and nitrogen-containing metabolites account for 7.7 and 36.1 %, respectively.…”
Section: Structural Classificationmentioning
confidence: 99%
“…Overall, the geometries of double bonds in 1-6 were determined, but the absolute configurations of chiral centers were not assigned. Most of the halogenated bisabolane sesquiterpenes featured halogens at C-2 and C-3 (Wang et al 2013), but the majority of the nonhalogenated ones were Fig. 1 Carbon skeletons of the nonhalogenated sesquiterpenes from Laurencia (*devoid of halogenated members)…”
Section: Bisabolanesmentioning
confidence: 99%
“…After that, a large number of other interesting structures have been characterized along with the improvement of isolation, identification, and bioassay techniques, and overall more than 700 organic molecules were reported from this genus so far (Blunt et al 2013;Faulkner 1977). Among them, the halogenated compounds (more than 500) were often the subjects of previous reviews, and they really exhibited high molecular diversity and intriguing bioactivity (Wang et al 2013). However, the nonhalogenated products with diverse skeletons also occurred widely in Laurencia species, and some of them related to the halogenated ones in biogenesis and showed potent biological activities.…”
Section: Introductionmentioning
confidence: 99%
“…It is estimated that over 60 species throughout the world have been investigated and more than 700 compounds possessing unique structural features have already been isolated from red algae of genus Laurencia [4]. In particular, species of Laurencia are known to be the richest producers of halogenated secondary metabolites with diverse and unique structural features depending on species, localities and season [5]. Laurencia species produce bromine-containing compounds in much larger numbers than either chlorine-or iodine-containing ones whereas, the Clcontaining compounds usually also possess Br atom(s) [6].…”
Section: Introductionmentioning
confidence: 99%