Mycochemistry of marine algicolous fungi

Ji, Nai‐Yun; Wang, Bin‐Gui

doi:10.1007/s13225-016-0358-9

Cited by 50 publications

(44 citation statements)

References 199 publications

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“…Most of the algicolous fungi distributed in the genera of Aspergillus and Penicillium , which belong to the facultative marine fungi that were frequently discovered from different groups of algae [1,2]. However, four strains of the fungal genus Eurotium including E. cristatum [3], E. rubrum [4], Eurotium sp.…”

Section: Introductionmentioning

confidence: 99%

Indolediketopiperazine Alkaloids from Eurotium cristatum EN-220, an Endophytic Fungus Isolated from the Marine Alga Sargassum thunbergii

et al. 2017

Marine Drugs

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Four new indolediketopiperazine derivatives (1–4), along with nine known congeners (5–13), were isolated and identified from the culture extract of Eurotium cristatum EN-220, an endophytic fungus obtained from the marine alga Sargassum thunbergii. The structures of thesecompounds were elucidated on the basis of extensive spectroscopic analysis and the absolute configurations of compounds 1–4 were established by NOESY experiments and by chiral HPLC analyses of their acid hydrolysates. The absolute configuration of C-8 (a quaternary carbon substituted with a hydroxyl group) in 5 of preechinulin class was firstly determined by electronic circular dichroism (ECD) calculations. All these compounds were evaluatedfor brine shrimp (Artemia salina) lethality and nematicidal activity as well as antioxidativeand antimicrobial potency.

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Section: Introductionmentioning

confidence: 99%

Indolediketopiperazine Alkaloids from Eurotium cristatum EN-220, an Endophytic Fungus Isolated from the Marine Alga Sargassum thunbergii

et al. 2017

Marine Drugs

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“…6 Algae are a major source of marine derived fungi and the chemistry of these organisms has been reviewed. 7 A comprehensive review discusses the diversity of holothurian triterpene glycosides and their bioactivities reported over the last six decades. 8 The diterpenoid chemistry of gorgonians and the diverse chemistry derived from Spongia species have been reviewed.…”

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confidence: 99%

Marine natural products

et al. 2018

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Covering: 2016. Previous review: Nat. Prod. Rep., 2017, 34, 235-294This review covers the literature published in 2016 for marine natural products (MNPs), with 757 citations (643 for the period January to December 2016) referring to compounds isolated from marine microorganisms and phytoplankton, green, brown and red algae, sponges, cnidarians, bryozoans, molluscs, tunicates, echinoderms, mangroves and other intertidal plants and microorganisms. The emphasis is on new compounds (1277 in 432 papers for 2016), together with the relevant biological activities, source organisms and country of origin. Reviews, biosynthetic studies, first syntheses, and syntheses that led to the revision of structures or stereochemistries, have been included.

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“…All plants in natural ecosystems studied to date appear to be symbiotic with fungal endophytes [22,23]. Regarding to the marine environment, endophytes can be found in associations with seaweed and represent an ecologically defined group of marine-derived organisms denominated Marine Algicolous Fungi (MAFs) [24]. These organisms benefit from this ecological relation usually getting nutrition and protection from the host organism, in return, endophytes play important roles in the ecological adaptation of their host, such as increasing environmental stress tolerance, improving plant vigor and decreasing herbivore attack by producing certain secondary metabolites [25,26].…”

Section: Endophytic Fungimentioning

confidence: 99%

Antitumor Potential of Seaweed Derived-Endophytic Fungi

et al. 2019

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The marine environment presents a high biodiversity and a valuable source of bioactive compounds with therapeutic and biotechnological potential. Among the organisms present in marine environment, the endophytic fungi isolated from seaweed stand out. These microorganisms have aroused interest in the scientific community regarding its various activities such as antiviral, antimicrobial, antioxidant, photoprotective, cytotoxic, genotoxic, anti-inflammatory, and anticancer, besides establishing important ecological relations with its hosts. Anticancer molecules derived from marine natural sources are a promising target against different types of cancer. The disease’s high rates of morbidity and mortality affect millions of people world wild and the search for new therapeutic alternatives is needed. Thus, this review partially summarizes the methodologies for the isolation of seaweed-derived endophytic fungi, as well as describes the anticancer compounds isolated from such microorganisms, reported in the literature from 2009 to the present. In addition, it describes how some biotechnological processes can help in the discovery of bioactive compounds, especially with anticancer activity.

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Mycochemistry of marine algicolous fungi

Cited by 50 publications

References 199 publications

Indolediketopiperazine Alkaloids from Eurotium cristatum EN-220, an Endophytic Fungus Isolated from the Marine Alga Sargassum thunbergii

Indolediketopiperazine Alkaloids from Eurotium cristatum EN-220, an Endophytic Fungus Isolated from the Marine Alga Sargassum thunbergii

Marine natural products

Antitumor Potential of Seaweed Derived-Endophytic Fungi

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