Handling elevates the colonic temperature of mice

Body temperatures of house mice artificially selected for high voluntary wheel-running behavior: repeatability and effect of genetic selection

“…The delay time required for capture and measurement was always included because handling has been shown to in¯uence body temperature (Cabanac and Briese, 1992). Time of day and z-transformed time of day squared were always included because body temperature follows a circadian rhythm (Re®netti and Menaker, 1992); the squared term was used to account for the non-linear relationship and z-transformation was applied to avoid correlation between the predictors (orthogonal polynomial).…”

Brain temperature measurement and regulation in awake and freely moving rodents

“…The two-vessel occlusion model (2-VO) of global ischemia in rat is thought to produce delayed hyperthermia [16], but these findings have not been confirmed with telemetry temperature probes. Given that rectal temperature probes cause a rise in body temperature (stress-induced fever) [22] such findings in the 2-VO should be confirmed with radiotelemetry. Focal ischemia in rat is also thought to cause hyperthermia [17,18], aggravating injury.…”

“…Such differences are likely due to model differences (e.g., involvement of hypothalamus), but may also, in part, be related to the method of measuring temperature. For example, rectal probe insertion, which causes temperature to rise [22], may affect ischemic and normal animals differently. In gerbils subjected to unilateral common carotid artery occlusion (Colbourne and Auer, unpublished data), those that suffered a focal ischemic insult experienced a variable postoperative temperature profile with sometimes-marked fluctuations between normothermia and hypothermia (e.g., 32°C).…”

Temperature measurements

“…In nonanesthetized rodents, T core accurately reflects T brain (Dilsaver et al 1992;. However, obtaining T rec , which estimates T core in conscious rodents, causes a stress-induced fever (SIF), which is due to an elevated temperature set-point resulting in a controlled rise in temperature (Kluger et al 1987;Briese and Cabanac 1991;Cabanac and Briese 1992). This SIF has not been examined in the gerbil, which is commonly used to model global ischemia .…”