Handwriting and pre-frailty in the Lausanne cohort 65+ (Lc65+) study

Association between adiposity and disability in the Lc65+ cohort

“…The Lc65+ cohort has been described previously (36)(37)(38)(39). Briefly, a population-based sample of residents of Lausanne aged 65-70 years were invited to be examined and enrolled in the cohort in 2005.…”

A Smart Ink Pen for the Ecological Assessment of Age-Related Changes in Writing and Tremor Features

“…On the other hand, the assessment of the paper-and-pen technique requires the expertise of a clinical professional to evaluate the writing outcome without the support of any quantitative data: such an approach does not match the current needs of the health systems that count on the achievements of telemedicine to solve problems such as the limited availability of specialists, the reduced time to conduct such tests, and the difficulty for some patientsespecially the older onesto reach the examination site [7]. For this reason, in most of the recent studies, the paper-and-pen approach was replaced by digitizers and tablets able to return the 2D trajectory of the writing trace [6], [8], [9]. The digitalization of data allows extracting quantitative parameters to objectively assess handwriting and achieving remote monitoring of user's performance.…”

“…Another element of newness of our approach is the ecological validity and the transparency of the protocol. Indeed, differently from the vast majority of literature [6], [7], [8], [9], in which handwriting is studied under controlled conditions (with the subject copying or writing previously defined text), we decided to propose tasks mimicking daily-life writing without constraining the writing modality or content.…”

Determinants of Quality of Life in Pre-Frail Older Adults According to Phenotypic Criteria: the VERISAUDE Study

“…Further exploring pre-frailty status is critical because a high percentage of community-dwelling older adults are pre-frail (being the most common criteria, a low grip strength (95.0% in Lorenzo-López et al 2016;about 45% in Drey et al 2011) or self-reported exhaustion (70.2%, Chang et al 2012)), showing an increased risk of progressing to frailty in the next years. It has been previously reported that an increased number of phenotypic frailty criteria increases risk of mortality (Kulminski et al 2008), to have medical conditions and to require assistance in activities of daily living (Camicioli et al 2015). Older populations in the transition from a robust to a frail status have been investigated to a lesser extent than frail populations (see Fernández-Garrido et al 2014, for a recent review).…”