Hantaran Sinyal Leptin dan Obesitas: Hubungannya dengan Penyakit Kardiovaskuler

Limanan, David

doi:10.23886/ejki.1.2063.144-155

Cited by 8 publications

(10 citation statements)

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“…The use of more energy will make the need for oxygen much greater which will spur the heart to work harder. This can be experienced in someone who has an excess body mass index (Limanan and Prijanti, 2013).…”

Section: Rp Tenenbaum 2014)mentioning

confidence: 99%

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Relationship of Body Mass Index (BMI) and Sex in Adolescent Training Resistance

Ratna¹

2021

GASTER

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Adolescents 18-21 years of age today have problems related to movement that result in changes to resistance training. Exercise resistance is expressed in VO2max. Body mass index and gender are factors that influence VO2max. The purpose of this study is to analyze the relationship between body mass index and sex on VO2Max and to analyze how closely the relationship is. The type of this study is an observational study with a purposive sampling technique with a point time approach design with a total of 183 samples with criteria for healthy samples aged 18- 21 years. The independent variable in this study was exercise endurance (VO2max), and the dependent variable was body mass index and gender. The data is processed using software for data analysis. From the data normality test using Kolmogorov Smirnov for Body Mass Index data with a value of 0.001, sex data with a value of 0.000, VO2Max data with a value of 0.000 which indicates abnormal data. Test Data analysis using the Spearman rank test resulted in the value of gender and VO2max 0.001 with r value of 0.203 and body mass index value and VO2max -0.015 with r value of 0.766.There is a correlation between body mass index and sex on VO2Max.

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Section: Rp Tenenbaum 2014)mentioning

confidence: 99%

“…With the higher leptin in the blood, the binding of leptin to the receptors also causes more contraction of the cardiomyocytes to decrease (Limanan and Prijanti, 2013). The reduced contraction of cardiomyocytes will cause the supply of O2 to the body muscles to also decrease (Wibowo, C. dan Dese, 2019).…”

Section: Vo2max In Adolescentsmentioning

confidence: 99%

Relationship of Body Mass Index (BMI) and Sex in Adolescent Training Resistance

Ratna¹

2021

GASTER

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“…Pola makan yang salah berdampak pada munculnya masalah gizi seperti obesitas. Limanan (2013) mengatakan Orang yang obesitas mengalami peningkatan jalur ROS, ROS merupakan radikal bebas turunan oksigen yang sangat reaktif. Radikal bebas adalah atom yang kehilangan pasangan elektronnya, radikal bebas sangat tidak stabil dan bergerak dengan cepat.…”

Section: Pendahuluanunclassified

Formulation of Flakes Bran Flour Substitution with Fortified Zinc for Fertile-Age Women

Ulfa

Marjan

Maryusman

2018

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<p>There are about 32.9% Indonesian women susceptive to obesity and free radical exposure. Free radicals are resistible to Zn-cofactors and a-tocopherols. The aims of this study was to make flakes formulations with zinc fortification, then analyze the physical and chemical character of flakes (hardness and color degree), and analyze carbohydrate, protein, fat, zinc, and α-tocopherol. The experimental design used for this study was a complete randomized design. The results showed the best formulas that substitution by bran was 25 % and fortified seng was 118,9 mg. The chemical properties of the best formulas should has increased the levels of protein, fat, and Zinc. One serving (55g) of flakes has 208,4 Kal; 3,38 g protein; 0,27 g fat; 48,12 g carbohydrate ; 1,89 mg seng; and 3,53mg α-tocopherol.</p>

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“…Estrogen berpengaruh pada regulasi dan metabolisme lemak (Oosthuyse and Bosch, 2012), sehingga penurunan kadar estrogen akan berpengaruh pada jumlah lemak tubuh (Razali, 2008, Muljadi, 2011, Cornelli, 2013. Leptin mempunyai peran penting dalam signaling yang mengatur homeostastis energi baik secara sentral maupun perifer, mengurangi nafsu makan, massa jaringan leptin meregulasi BB melalui kerja di hipothalamus dengan efek mengurangi nafsu makan sehingga dapat menurunkan berat badan (Limanan and Prijanti, 2013).…”

Section: Penggunaan Depo Progestinunclassified

Upaya Mencegah Efek Samping Penggunaan Kontrasepsi Depo Progestin Dengan Ekstrak Teh Hijau

Wahyuni¹

2017

GASTER

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Latar belakang: Kontrasepsi injeksi lebih banyak digunakan di masyarakat adalah suntikan Depo-medroxiprogesteron Asetat (DMPA) atau lebih dikenal sebagai Depo progestin. Penggunaan Depo Progestin jangka panjang dapat menyebabkan efek peningkatan berat badan melalui akumulasi lemak visceral dan perubahan kadar hormon leptin. Diperlukan suplemen untuk mencegah efek samping dari penggunaan kontrasepsi dengan menggunakan teh hijau. berat badan. Tujuan: membuktikan ekstrak teh hijau dalam menurunkan jumlah lemak viseral dan menurunkan kadar leptin pada tikus putih (Rattus norvegicus wistar) yang dipapar kontrasepsi suntik Depo Progestin. Metode: Experimental laboratorik dengan post test only control group design. Sampel Rattus norvegicus Wistar 25 ekor, dibagi menjadi 5 kelompok. Kelompok kontrol negatif (di suntik aquades 0,2ml/minggu), kontrol positif (disuntik Depo Progestin 2,7 mg/minggu), kelompok perlakuan I (disuntik Depo Progestin 2,7 mg dan disonde dan disonde ekstrak teh hijau dosis 21,6 mg/tikus), kelompok perlakuan III (disuntik Depo Progestin 2,7 mg dan disonde ekstrak teh hijau dosis 43.2 mg/hari). Tikus diadaptasi selama 7 Hasil: efek ekstrak teh hijau pada berat sebesar 0.206 dengan p-value sebesar 0.322, P-value lebih dari 0.05. Kesimpulan: Ekstrak teh hijau tidak berpengaruh terhadap berat lemak viseral namun berpengaruh menurunkan kadar leptin pada tikus putih yang dipapar Depo Progestin. Tidak terdapat hubungan yang Kata kunci: depo progestin, lemak visceral, leptin, teh hijau ABSTRACT Injection is more widely used is the injection of Depo-medroxiprogesteron Acetate (DMPA) or of weight gain through the accumulation of visceral fat and changes in hormone levels of leptin. Necessary supplements to prevent side effects of contraceptive use by using green tea. Objective: to prove the effects of green tea against the increase and decrease visceral fat hormone leptin in mice that dipapat depot progestin. Methods: Experimental laboratory with post test only control group design. Samples are Rattus norvegicus Wistar 25 animals, divided into 5 groups. Negative control group (injected with distilled water 0,2ml / week), positive

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Hantaran Sinyal Leptin dan Obesitas: Hubungannya dengan Penyakit Kardiovaskuler

Cited by 8 publications

References 0 publications

Relationship of Body Mass Index (BMI) and Sex in Adolescent Training Resistance

Relationship of Body Mass Index (BMI) and Sex in Adolescent Training Resistance

Formulation of Flakes Bran Flour Substitution with Fortified Zinc for Fertile-Age Women

Upaya Mencegah Efek Samping Penggunaan Kontrasepsi Depo Progestin Dengan Ekstrak Teh Hijau

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