Hantzsch reaction on free nano-Fe2O3 catalyst: excellent reactivity combined with facile catalyst recovery and recyclability

Abstract

A magnetic nanoparticle catalyst was readily prepared from inexpensive starting materials which catalyzed the Hantzsch reaction. High catalytic activity and ease of recovery from the reaction mixture using an external magnet, and several reuse times without significant losses in performance are additional eco-friendly attributes of this catalytic system.

A Flexible one-pot synthesis of pyrazolopyridines catalyzed by Fe3O4@SiO2-SO3H nanocatalyst under microwave irradiation

“…The chemical synthesis productivity can be enhanced by nano-sized catalysts due to their small size and high surface-to-volume ratios [13][14][15][16]. Magnetic materials have emerged as a suitable group of heterogeneous catalysts owing to their numerous applications in synthesis and catalysis [17][18][19]. The surface functionalization of magnetic particles is an elegant way to bridge the gap between heterogeneous and homoge-neous catalyses [20][21][22].…”

A solvent-free synthesis of polyhydroquinolines via Hantzsch multicomponent condensation catalyzed by nanomagnetic-supported sulfonic acid

“…[8][9][10][11][12][13][14][15] All mentioned cases demonstrate clearly the remarkable potential of the polyhydroquinoline derivatives as a source of valuable drugs. 16,17 In continuation of our investigation on the use of nano-g-Fe 2 O 3 -SO 3 H as catalyst for MCRs and our interest in synthesis of heterocycles containing a nitrogen atom, 18,19 we report an efficient and facile synthesis of hexahydroquinolines under solvent-free conditions (Scheme 1).…”

Nano-Fe3O4-encapsulated silica particles bearing sulfonic acid groups as a magnetically separable catalyst for green synthesis of 1,1-diacetates

“…Nowadays study of nano-scale materials is gaining importance in modern organic chemistry due to its exclusive properties such as easy and efficient separation from the final product using an external magnet (20), high level of catalytic activity (21,22), simple filtration, reusable, low cost, non-toxic, and insolubility in reaction media (23).…”