Haptoglobin Types in South-East Asia

The Distribution of Haptoglobin and Transferrin Groups in South and South East Asia

“…Two investigations in Japan (Yamagtichi et al, 1959;Malsunaga and M urai, 1960) give a mean frequency for the H p1 gene of 0.26 whereas values from various places in Oceania and New Guinea range from 0.50 to 0.66 (Harris et al, 1959;Blumberg, 1959;Douglas arid Stavely, 1960;Bennett et al, 1960). Low values of the Hp1 gene frequency have been reported previously from this laboratory for Chinese, Malays and Indians in Malaya (Kirk et al, 1960) the value of 0.09 for the sample of Indians being the lowest value reported so far. Similar low values of H p1 have also been found in Australian aborigines, although evidence is accumulating for con siderable variation in frequency among different tribes (Kirk and Lai, unpublished).…”

“…Asia. The techniques employed in collecting the samples and determ ining the Hp and T f phenotypes were esentially the same as those described previously (Kirk et al, 1960) w ith the exception th at the vertical starch-gel technique wras used throughout. The lip 1 gene frequency has been deter mined by direct gene counting and om itting the Hp 0 phenotypes from the calculation.…”

Genetic evidence of gene flow from Indians to Malays

“…Most studies characterize the populations of south India by low frequencies of the Hp 1 allele, ranging from 5.9~ to 16.9~, except in the Todas whose frequency is 35~ . The Indians of Malaysia have lip 1 frequences of 9.2~ and 10.1~ (Steinberg et al, 1961;Kirk et al, 1960), similar to those of the south Indian populations.…”

“…The Hp ~ frequencies for Malays and Indonesians are almost identical, about 30~ in both populations (Kirk et al, 1960;Lie-Injo et al, 1968); the Chinese of Malaysia have Ilp ~ frequencies of 27~ and 29~ (Kirk et al, 1960;Steinberg et al, 1961). However, in a survey of Malays from Perlis, a northern state of Peninsular Malaysia, Kirk et al (1960) found a lower Hp 1 frequency of 20~ for Malays.…”

“…However, in a survey of Malays from Perlis, a northern state of Peninsular Malaysia, Kirk et al (1960) found a lower Hp 1 frequency of 20~ for Malays. In the same survey, they found Indians in Perlis have a Hp 1 frequency of about 9~.…”