1990
DOI: 10.1097/00006123-199010000-00017
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Harvey Cushing and pediatric neurosurgery

Abstract: Harvey Cushing made fundamental and seminal contributions to pediatric neurosurgery. Early in his surgical career, he described the diagnosis and treatment of subdural hematomas in newborn infants. Important investigations on the cerebrospinal fluid and the nature of hydrocephalus were carried out under his direction, first by Walter Dandy and Kenneth Blackfan in the Hunterian Laboratory at the Johns Hopkins School of Medicine, and shortly afterward by Lewis Weed at the Laboratory of Surgical Research at Harva… Show more

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Cited by 12 publications
(5 citation statements)
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“…Harvey Cushing, working with Weed, can also be credited for popularizing the idea of the arachnoid granulations as the site of CSF resorption. Weed reproduced and modified earlier experiments of Key and Retzius in which a gelatin solution colored with Berlin blue dye was injected into the lumbar subarachnoid space in human cadavers and observed to pass through the arachnoid granulations into the venous sinuses as well as through lymphatic vessels into the frontal sinus and nasal membranes [6] . Interestingly, Dandy was skeptical and challenged the concept of specialized structures being invoked to explain fluid resorption in the brain that seemed to occur in a similar fashion in other body cavities (e.g., pleura, peritoneum).…”
Section: The Contributions Of Harvey Cushingmentioning
confidence: 82%
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“…Harvey Cushing, working with Weed, can also be credited for popularizing the idea of the arachnoid granulations as the site of CSF resorption. Weed reproduced and modified earlier experiments of Key and Retzius in which a gelatin solution colored with Berlin blue dye was injected into the lumbar subarachnoid space in human cadavers and observed to pass through the arachnoid granulations into the venous sinuses as well as through lymphatic vessels into the frontal sinus and nasal membranes [6] . Interestingly, Dandy was skeptical and challenged the concept of specialized structures being invoked to explain fluid resorption in the brain that seemed to occur in a similar fashion in other body cavities (e.g., pleura, peritoneum).…”
Section: The Contributions Of Harvey Cushingmentioning
confidence: 82%
“…This led to dilation of the contralateral lateral ventricle and collapse of the plexectomized ventricle. Based on this, Dandy concluded with "absolute proof" that the choroid plexus is the primary site of CSF production [6] . This led to several attempted treatments of hydrocephalus that involved surgical choroid plexectomy, but the results were overwhelmingly disappointing [7,8] .…”
Section: Walter Dandy's Hydrocephalusmentioning
confidence: 99%
“…1-8 Although he is best known for his work on brain tumors and intracranial pressure, 9-15 Cushing also made contributions to cerebrovascular neurosurgery, 16,17 radiology, 18 anesthesia, 19 and endocrinology. 20 Despite the role that Cushing played in the development of the field of neurosurgery, few know that Cushing was also a spine surgeon.…”
mentioning
confidence: 99%
“…Bailey began by going through the specimens as they came into the laboratory and arranging them in groups according to length of the patient's survival. 24 Based on the predominant cellular configuration, Bailey classified these tumors into 13 categories. 32 All in all, Bailey exhaustively examined and classified the pathological material and records of a total of 414 cases of glioma in Cushing's series and performed histological tissue studies in 254 of these.…”
mentioning
confidence: 99%
“…24 In 1926, the completed monograph by Bailey and Cushing, A Classification of the Tumors of the Glioma Group on a Histogenetic Basis with a Correlated Study of Prognosis, was published. The results of the glioma studies were first reported by Cushing in the Cameron Prize Lectures given at the University of Edinburgh in October of 1925.…”
mentioning
confidence: 99%