Has Helicobacter pylori eradication therapy any effect on severity of rosacea symptoms?

Abstract

References1 Friboes W. Beitrag zur Klinik und Histopathologie der gutartigen Hautepitheliome . S. Karger-Verlag, Berlin, 1912. 2 Kleine-Natrop HE. Simultaneous generalization of benign basalioma of both Spiegler and Brooke types. Arch Klin Exp Dermatol 1959; 209 : 45 -55. 3 Volter C, Baier G, Schwager K et al. Cylindrocarcinoma in a patient with Brooke-Spiegler syndrome. Laryngorhinootologie 2002; 81 : 243 -246. 4 Durani BK, Kurzen H, Jaeckel A et al. Malignant transformation of multiple dermal cylindromas. Br J Dermatol 2001; 145 : 653 -656. 5 Pizinger K, Michal M. Malignant cylindroma in Brooke-Spiegler syndrome. Dermatology 2000; 201 : 255 -257. 6 McKee PH, Fletcher CD, Stavrino P, Pambakian H. Carcinosarcoma arising in eccrine spiradenoma. Am J Dermatopathol 1990; 12 : 335 -343. 7 Grouls V, Iwaszkiewicz J, Berndt R. Malignes ekkrines Spiradenom. Z Hautkr 1991; 66 : 892-895. 8 Meriggi F, Tagliabo R, Morone G et al. The potential malignancy of eccrine spiradenoma. Ital J Surg Sci 1989; 19 : 265 -268. 9 Biernat W, Peraud A, Wozniak L, Ohgaki H. P53 mutations in sweat gland carcinomas. Int J Cancer 1998; 76 : 317 -320. 10 Mutoh H, Nagata H, Ohno K et al. Analysis of the p53 gene in parotid gland cancers: a relatively high frequency of mutations in low-grade mucoepidermoid carcinomas. Int J Oncol 2001; 18 : 781-786. References 1 Hull PR, D'Arcy C. Isotretinoin use and subsequent depression and suicide: presenting the evidence. Am J Clin Dermatol 2003; 4: 493 -505. 2 Bremner JD. Does isotretinoin cause depression and suicide? Psychopharmacol Bull 2003; 37: 64 -78. 3 O'Connell KA, Wilkin JK, Pitts M. Isotretinoin (Accutane) and serious psychiatric adverse events. J Am Acad Dermatol 2003; 48: 306 -308. 4 Chu A, Cunliffe WJ. The inter-relationship between isotretinoin/ acne and depression. J Eur Acad Dermatol Venereol 2003; 17: 619. 5 Gupta MA. Incidence of psychiatric disorders in dermatological patients. J Eur Acad Dermatol Venereol 2003; 17: 624 -626. 6 Jacobs DG, Deutsch N, Brewer M. Suicide, depression, and isotretinoin: is there a causal link? J Am Acad Dermatol 2001; 45: S168 -S175. 7 Wysowski DK, Pitts M, Beitz J. An analysis of reports of depression and suicide in patients treated with isotretinoin. J Am Acad Dermatol 2001; 45: 515 -519. 8 Jick SS, Kremers HM, Vasilakis-Scaramozza C. Isotretinoin use and risk of depression, psychotic symptoms, suicide, and attempted suicide.

Rosacea and gastrointestinal disorders: a population‐based cohort study

“…17 Furthermore, the increased prevalence of HPI is reasonably well established and although the risk of new-onset HPI was not increased among patients with rosacea, the baseline prevalence of HPI was significantly higher (P < 0Á001) among patients with rosacea. 12,14,[29][30][31][32][33][34][35] Lastly, the association between rosacea and IBS has not been previously reported, but is in accordance with the complaints (in particular a bloated feeling) that we frequently hear from our patients with rosacea. However, we cannot exclude that some patients may have been incorrectly diagnosed with IBS as they may instead have been suffering from one of the other studied conditions.…”

“…Moreover, the observed significant association between rosacea and CeD is in agreement with one recent GWAS study that showed shared genetic risk loci for these two conditions . Furthermore, the increased prevalence of HPI is reasonably well established and although the risk of new‐onset HPI was not increased among patients with rosacea, the baseline prevalence of HPI was significantly higher ( P < 0·001) among patients with rosacea . Lastly, the association between rosacea and IBS has not been previously reported, but is in accordance with the complaints (in particular a bloated feeling) that we frequently hear from our patients with rosacea.…”

Diseases of cutaneous appendages

“…1348 Acne rosacea has been reported in patients with HIV infection. [1358][1359][1360][1361][1362][1363] A rosacea-like eruption has also occurred with Candida albicans infection. [1355][1356][1357] It is likely that the treatment used for H. pylori is beneficial for rosacea.…”

Rosacea and its comorbidities

“…Improvment in the symptomatology of the disease noticed after the treatment of HP infection is supported by several studies, while other authors consider that this treatment and RS evolution are not connected (8,9). Some authors go even further and claim that RS is in fact an extragastric manifestation of HP infection (2,10,11).…”