2000
DOI: 10.1002/1098-2272(200007)19:1<1::aid-gepi1>3.0.co;2-e
|View full text |Cite
|
Sign up to set email alerts
|

Haseman and Elston revisited

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

2
283
0

Year Published

2001
2001
2014
2014

Publication Types

Select...
5
4

Relationship

0
9

Authors

Journals

citations
Cited by 311 publications
(285 citation statements)
references
References 31 publications
2
283
0
Order By: Relevance
“…30,32,33 In this model, the mean-corrected trait product for a sib pair is regressed on the underlying IBD-sharing proportions at different loci as predictors. To account for the dependencies among multiple sib pairs created from the same family, we incorporated the method of generalized estimating equations (GEE) into H -E regression analyses using GENMOD procedures in SAS (v8.2).…”
Section: Epistatic Interaction Analyses Of Qualitative Traitsmentioning
confidence: 99%
“…30,32,33 In this model, the mean-corrected trait product for a sib pair is regressed on the underlying IBD-sharing proportions at different loci as predictors. To account for the dependencies among multiple sib pairs created from the same family, we incorporated the method of generalized estimating equations (GEE) into H -E regression analyses using GENMOD procedures in SAS (v8.2).…”
Section: Epistatic Interaction Analyses Of Qualitative Traitsmentioning
confidence: 99%
“…In addition to the SEGPATH analyses, both single-point and multipoint linkage analyses were performed with the sib-pair linkage procedure (12,14) as implemented in the SIBPAL2 program of the SAGE 4.0 Statistical Package (28). Briefly, if there is a linkage between the marker locus and a putative gene influencing the phenotype, then sibs sharing a greater proportion of alleles identical-by-descent (IBD) at the marker locus also will show a greater resemblance in the phenotype.…”
Section: Subjectsmentioning
confidence: 99%
“…49 For linkage analyses, extended Haseman ± Elston regression analyses were performed using the computer program SIBPAL2 available in SAGE 4.0. 50,51 This program models full and half sibpair covariance as a function of marker allele identity by descent (IBD) sharing by allowing single or multipoint estimates of the proportion of alleles shared IBD. The extended Haseman ± Elston regression model increases the power to detect linkage by changing the dependent variable from the squared difference to the mean-corrected product of the sib's trait values.…”
Section: Statistical Analysesmentioning
confidence: 99%
“…The extended Haseman ± Elston regression model increases the power to detect linkage by changing the dependent variable from the squared difference to the mean-corrected product of the sib's trait values. 51 …”
Section: Statistical Analysesmentioning
confidence: 99%