Hazards of Drug Use Among the Elderly

Krupka, Lawrence R.; Vener, Arthur M.

doi:10.1093/geront/19.1.90

Cited by 36 publications

(10 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although it is true that developing organisms may be of special sensitivity simply because they are developing, whether environmental contaminants are having a disproportionate impact on the young is a matter primarily of conjecture (with some obvious exceptions, such as lead). However, much is known about the special sensitivity of the elderly to pharmacologic agents (69), and the elderly have also been viewed as a population at special risk from environmental insult due to their enhanced sensitivity (70). An argument could be made on that basis that an extra 10× factor is needed to protect the elderly as well as the young.…”

Section: Discussionmentioning

confidence: 99%

Children's Health, Susceptibility, and Regulatory Approaches to Reducing Risks from Chemical Carcinogens

Charnley¹,

Putzrath²

2001

Environmental Health Perspectives

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Children's Health, Susceptibility, and Regulatory Approaches to Reducing Risks from Chemical Carcinogens

Charnley¹,

Putzrath²

2001

Environmental Health Perspectives

View full text Add to dashboard Cite

“…The number of drugs administered simultaneously is directly proportional to the chance of experiencing a drug interaction (Krupka & Vener 1979).…”

Section: Adverse Drug Effectsmentioning

confidence: 99%

“…Since only 4 to 5% of elderly people live in institutional settings, lack of supervision in monitoring drug regimens is also a factor in poor compliance (Krupka & Vener 1979). Inability to manage their medications at home was the reason for 23% of nursing home admissions (Green et al 1986).…”

Section: Compliancementioning

confidence: 99%

The Pharmacist??s Role in Rational Drug Therapy of the Aged

Adamcik

Rhodes

1993

Drugs & Aging

View full text Add to dashboard Cite

“…Disease and pharmacologic management of disease may impair perception, limit judgment, and restrict mobility. Medications prescribed for elderly people for more than one condition, by more than one clinician, increase the risk of drug reactions; there are differences in absorption, distribution, metabolism, and excretion and in receptor site activity 50 . While not all old people are ill, two thirds of those over 64 report one or more chronic condition, and most experience some decrement in vision, hearing, smell, reaction time, and physical strength.…”

Section: Thermal Injuriesmentioning

confidence: 99%

Injury in Late Life

Hogue

1982

J American Geriatrics Society

View full text Add to dashboard Cite

Epidemiologic studies show that injury is a nonrandom event of considerable consequence to older people. Even though children have the highest injury rates for all injuries combined, the elderly have the highest death rates and the highest dysfunction and disability rates from falls, fires and contact with hot substances, and vehicular crashes. There are notable race and sex differences in injuries in the elderly. Women have higher rates of injury from falls than men. Men have higher injury rates from burns and motor vehicle crashes (including pedestrian injuries), and for each of the three categories of injury men have higher death rates than women. Before the age of 75, nonwhite males have the highest rates of death from injury. At 75, however, white males cross over to have a much higher rate of death from injury than do nonwhite males. More than half the deaths due to unintentional injury in persons 65 and older are caused by falls. White men have the highest death rates from falls, followed by white women. More than a fourth of the injury fatalities for people 65 and older are from motor vehicle crashes. More than 9.3 per cent of all licensed drivers are 65 or older. Older drivers drive fewer miles than other people, and they tend to limit their driving to daytime and to relatively less stressful conditions. Nonetheless, when miles driven by drivers over 64 are taken into account, the relatively small number of crashes is equivalent to a crash rate exceeded only by the under‐25 age group. Pedestrian deaths account for more than a third of motor vehicle deaths to people 65 and older. The death rate from burns is higher in the elderly than in any other age group, including young children. In the event of thermal injury, old people are much less likely to survive. Diminished ability to perceive hazard and to respond effectively contributes to higher injury rates among the elderly, as does lower injury threshold.

show abstract

Hazards of Drug Use Among the Elderly

Cited by 36 publications

References 0 publications

Children's Health, Susceptibility, and Regulatory Approaches to Reducing Risks from Chemical Carcinogens

Children's Health, Susceptibility, and Regulatory Approaches to Reducing Risks from Chemical Carcinogens

The Pharmacist??s Role in Rational Drug Therapy of the Aged

Injury in Late Life

Contact Info

Product

Resources

About