HbA1c Levels among Primary Healthcare Patients with Type 2 Diabetes Mellitus in Oman

Al-Lawati, Jawad; Barakat, Mohammed N.; Al-Maskari, Masoud; Elsayed, Medhat K.; Al-Lawati, Alya M.; Mohammed, Ali Jaffer

doi:10.5001/omj.2012.111

Cited by 30 publications

(39 citation statements)

References 17 publications

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“…A highly significant correlation between HbA1c and FBS was noted in this study. 11 Similarly, significant correlations between HbA1c and TC were observed by Gimeno-Orna JA et al in a prospective cohort study which included 418 type 2 diabetics with follow-up until the appearance of cardiovascular disorders. 12 In this regard it is worth to state that small LDL-C particles are increased in diabetes and this metabolic indicator is indirectly reflected by LDL-C.…”

Section: Discussionmentioning

confidence: 85%

Relationship of Glycated Haemoglobin with Lipid Profile among Patients with Type 2 Diabetes Mellitus

2017

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Section: Discussionmentioning

confidence: 85%

Relationship of Glycated Haemoglobin with Lipid Profile among Patients with Type 2 Diabetes Mellitus

2017

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“…Some of these findings are supported by some, but not all, research. [Goudswaard et al 2004;Fox et al 2006;Ratsep et al 2010;Al-Lawati et al 2012;Angamo et al 2013]. …”

Section: Discussionmentioning

confidence: 99%

Level of A1C control and its predictors among Lebanese type 2 diabetic patients

Noureddine

Nakhoul

Galal

et al. 2014

Therapeutic Advances in Endocrinology

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Aim: Lebanon is among the top 10 countries with the highest prevalence of diabetes in the Middle East region with estimates reaching as high as 16.6% in adults aged 20-79 years. The objective of this study was to assess the level of A1C control among a cohort of type 2 diabetic patients and factors associated with uncontrolled A1C. Methods: We carried out a retrospective observational study among type 2 diabetes mellitus patients attending an outpatient endocrinologist's clinic between June 2008 and July 2012 in Beirut, Lebanon. Two groups were compared, based on their diabetic control (A1C < 7% and A1C ⩾ 7%). Results: A total of 551 patients were included in this study, where 31.8% attained A1C control. Crude analyses showed that some factors were significantly associated with uncontrolled A1C, and these were long-standing diabetes, diabetes-related complications, uncontrolled blood pressure, lipid profile, as well as the use of metformin, sulfonylurea, or insulin. When multivariate analysis was carried out, the chances of having uncontrolled A1C were significantly higher among patients who developed neuropathy (odds ratio [OR] 2.08, 95% confidence interval [CI] 1.11-3.90), had uncontrolled triglycerides (OR 1.98, 95% CI 1.33-2.94), used insulin (OR 4.52, 95% CI 2.32-8.83), and sulfonylureas (OR 2.88, 95% CI 1.88-4.40). Conclusion: Uncontrolled diabetes is more likely to exist in patients with neuropathy, uncontrolled triglycerides and those using insulin or sulfonylurea. Further research is needed to confirm the findings.

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“…The burden of diabetes has increased sharply in Oman over the last decade, rising from 8.3% in 1991 to 11.6% in 2000, and 12.3% in 2008 among adults aged 20 years and older [1, 2]. …”

Section: Introductionmentioning

confidence: 99%

Analysis of Inflammatory Mediators in Type 2 Diabetes Patients

Al-Shukaili

Al-Ghafri

Al-Marhoobi

et al. 2013

International Journal of Endocrinology

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107

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The main aim of this study is to assess the inflammatory markers in type 2 diabetes mellitus (T2DM) by measuring some cytokines concentrations and lymphocytes subset and correlate them with other laboratory investigations. Fifty-seven patients with type-2 diabetes and 30 healthy volunteers were enrolled in this study. Data for the C-reactive protein (CRP), haemoglobin, HbA1c, and autoantibody levels were obtained from the patients files. The cytokine concentrations were measured in patient's serum using commercially available ELISA assays. Lymphocytes subsets were measured by flow cytometric methods. The levels of IL-1β, IL-6, IL-15, and TNF-α were found to be decreased in T2DM patients, whereas the levels of IL-10, IFN-γ, and caspase-1 were increased, compared to normal controls. T2DM patients with hypertension show significantly decreased levels of IL-1β and caspase-1 compared to patients without hypertension. No significant differences in lymphocytes subset between cases and normal control were observed. Significant correlations were found between HbA1c and IL-6; body mass index (BMI) was significantly correlated with CRP, TNF-α, and phosphate; the weight (Wt) was associated with CRP and IFN-γ. In conclusion, an alteration in the function of the immune system was observed in T2DM patient.

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HbA1c Levels among Primary Healthcare Patients with Type 2 Diabetes Mellitus in Oman

Abstract: Younger Omani adults exhibit worse glycemic levels compared to older adults posing a formidable challenge to diabetes care teams.

Cited by 30 publications

References 17 publications

Relationship of Glycated Haemoglobin with Lipid Profile among Patients with Type 2 Diabetes Mellitus

Relationship of Glycated Haemoglobin with Lipid Profile among Patients with Type 2 Diabetes Mellitus

Level of A1C control and its predictors among Lebanese type 2 diabetic patients

Analysis of Inflammatory Mediators in Type 2 Diabetes Patients

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