HBr/H 2 O 2 -mediated formation of C–S bond with thiosulfates

Synthesis of substituted quinolines via B(C6F5)3‐catalyzed aniline‐aldehyde‐pyruvate oxidative annulation

“…Finally, 5u could be converted into DDD107498 according to the literature. [45] Based on our findings and the related references, [33][34][35][36][37][38][39][40][41][42][43][44] a plausible reaction mechanism for the present B(C 6 F 5 ) 3catalyzed aniline-aldehyde-pyruvate annulation reaction is depicted in Scheme 5. Upon heating, B(C 6 F 5 ) 3 is SCHEME 3 Substrate scope of B(C 6 F 5 ) 3 -catalyzed aniline-aldehyde-pyruvate reaction [Color figure can be viewed at wileyonlinelibrary.…”

“…[27][28][29][30][31][32] Moreover, B(C 6 F 5 ) 3 has been successfully employed in various other transformations. [33][34][35][36][37][38][39][40] One of the research hotspots is the boranecatalyzed multicomponent reactions (MCRs). Recently, a remarkable work made by Ingleson and coworkers covered a B(C 6 F 5 ) 3 -initiated aldehyde-aniline-alkyne reaction, which enabled the synthesis of various functionalized quinolines.…”

Visible‐Light‐Induced Hydroxysulfurization and Alkoxysulfurization of Styrenes in the Absence of Photocatalyst: Synthesis of β‐Hydroxysulfides and β‐Alkoxysulfides

“…These bis‐functionalization modes have shown synthetic convenience and efficiency due to the availability of starting materials without the required preformations . These transformations, however, could not occur without electrolysis auxiliary conditions, peroxide reagents,– a strong base, or a transitional metal, (Scheme a–1e). Accordingly, the ability to find simple and green methods to accomplish such difunctionalization of alkenes to prepare β‐oxy sulfides holds scientific merit.…”

Synthesis and Antifungal Activity of β-Hydroxysulfides of 1,3-Dioxepane Series

“…β-Hydroxysulfides are attractive tools in organic synthesis, which are actively used in the synthesis of allylic alcohols, cyclic sulfides, thioketones, and physiologically active compounds [1][2][3][4][5]. Products of their oxidation, β-hydroxysulfones, are useful reagents for preparation of lactones [6], 2,5disubstituted tetrahydrofuranes [7], and vinyl sulfones [8].…”

“…e same group of researchers reported several N-sulfonyl-tetrahydro [1,3]dioxepino [5,6] azirines which also possessed hypoglycemic activity [11]. Optically active derivatives of 1,3-dioxepan-5-ol were described as flexible analogs of a known HIV-1 protease inhibitor (PI) darunavir [12].…”