2021
DOI: 10.1111/evj.13455
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hCG is more effective than the GnRH agonist buserelin for inducing the first ovulation of the breeding season in mares

Abstract: Background Human Chorionic Gonadotropin (hCG) and Gonadotropin Releasing Hormone agonists (GnRHa) are routinely used to induce ovulation in mares. However, GnRHa efficacy in transitional mares has been suggested to be low. Objectives The aims of this study were as follows: (a) to compare the efficacy of hCG and GnRHa in inducing the first ovulation of the breeding season and (b) to evaluate the correlation between ovulatory response, uterine oedema and teasing score at the time of treatment during the early or… Show more

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Cited by 3 publications
(1 citation statement)
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“…1 It is therefore interesting to note that in the case of barren mares pre-treated with the dopamine antagonist, sulpiride ® (to accelerate the development of the first ovulatory follicle), hCG was considerably more reliable than a GnRH analogue in ensuring ovulation within 48 hours (90% vs 38%). 2 This is presumably because hCG works directly on the follicle (in a luteinizing hormone (LH)-like fashion), whereas a GnRH analogue must elicit LH release from the anterior pituitary. This further supports the supposition that the primary factor limiting ovulation during the spring transitional period is pituitary ability to generate an adequate LH surge, rather than inadequate follicular responsiveness to LH.…”
Section: En Suring S Permatozoa and Oo C Y Te Mee T At The Ri G Ht Time And Ri G Ht Pl Acementioning
confidence: 99%
“…1 It is therefore interesting to note that in the case of barren mares pre-treated with the dopamine antagonist, sulpiride ® (to accelerate the development of the first ovulatory follicle), hCG was considerably more reliable than a GnRH analogue in ensuring ovulation within 48 hours (90% vs 38%). 2 This is presumably because hCG works directly on the follicle (in a luteinizing hormone (LH)-like fashion), whereas a GnRH analogue must elicit LH release from the anterior pituitary. This further supports the supposition that the primary factor limiting ovulation during the spring transitional period is pituitary ability to generate an adequate LH surge, rather than inadequate follicular responsiveness to LH.…”
Section: En Suring S Permatozoa and Oo C Y Te Mee T At The Ri G Ht Time And Ri G Ht Pl Acementioning
confidence: 99%