Flow measurements through pipes and open channels are very important for the management of water resources effectively. Orifice meter is a very common and widely used flow measuring device in pipes as it is very cheap and simple compared with other devices, however, there are many parameters that affect its performance. Also, orifice is used as energy dissipation method in water hammer protection devices and hydroelectric power tunnels. So, experimental research is carried out in the Hydraulic Laboratory of Assuit University to study the effect of orifice geometry on the energy loss through it. Due to head losses occurring at the orifice, a coefficient of discharge (Cd) is used to calculate actual discharge from theoretical discharge. The experimental tests are carried out using four different types of orifice plates: circular, square, triangular, and hexagonal. For each one, the cross-sectional area is changed four times. The orifice is installed on a 10 cm diameter transparent pipe. The flow rate is changed ten times for each orifice. A general correlation equation is developed for the coefficient of discharge based on dimensional analysis. The research concludes that the triangular shape achieves high performance with a lower head loss and a higher coefficient of discharge when compared to the other orifice shapes.