Headache in Behçet's Syndrome

Abstract

Headache is the most common neurological symptom seen in BS, both in patients with and without neurological involvement. The results of our study reveal that headache is seen in a majority of patients with neurological involvement due to BS and in a minority with uveal inflammation. The prevalence of migraine and TTHA are close to the population in general, but a nonstructural migrainous headache, which is commonly associated with exacerbations with some of the systemic symptoms of the syndrome, is noteworthy in patients with BS. This form of headache is not specific for this disorder, but may be explained by a vascular headache triggered by the immunomediated disease activity in susceptible individuals.

Clinical characteristics of neuro-Behcet’s disease in Japan: a multicenter retrospective analysis

“…Headache is the most common neurological symptom seen in BD [4, 15]. Consistently, in the present study, headache and fever were observed in the majority of patients with acute NBD, whereas these symptoms were rare in patients with CP NBD.…”

“…Consistently, in the present study, headache and fever were observed in the majority of patients with acute NBD, whereas these symptoms were rare in patients with CP NBD. However, it should be pointed out that headache was present in 53.9% of the patients with acute NBD and 42.4% of the patients with non-NBD, consistent with previous findings that headache is also a common symptom in BD independent of neurological involvement [4, 15]. Therefore, it is difficult to delineate acute NBD versus non-NBD by the presence of headache alone.…”

Neuro-Behçet’s Disease: An Unusual Cause of Headache

“…Accompanying symptoms and triggers are less common in nonstructural headache than in migraine. 10 Third, approximately 10-15 % of headaches in BD are consistent with a diagnosis of NBD. 6 The prevalence of headache in NBD depends on the specific manifestation of neurological involvement.…”

“…6 These headaches do not meet the criteria for either NBD or a primary headache disorder. 10 Focal neurological findings and abnormal neuroimaging are noticeably absent. 10 Particular features of these headaches distinguish them from migraines.…”

“…10 Focal neurological findings and abnormal neuroimaging are noticeably absent. 10 Particular features of these headaches distinguish them from migraines. These headaches tend to occur with BD flares and improve with systemic corticosteroid therapy.…”