Healing by Secondary Intention of Auricular Defects After Mohs Surgery

Minimally Invasive Options for Cutaneous Defects: Secondary Intention Healing, Partial Closure, and Skin Grafts

“…Defects involving the lower lid margin heal acceptably if less than 50% of the lid is involved, and the defect is full thickness [48,49]. Healing of defects on the nose and the ear depends on the subsite [41,50]. The temple and scalp usually heal with acceptable results, with the exception of defects greater than 10 cm, which may result in fragile unstable scars.…”

Second intention healing after Mohs micrographic surgery

“…Multicentric re‐epithelialization starts later (7 days), but is not definitive to the total time of healing. 10 Loss of tight binding, fibronectin, formation of a provisional matrix and laminin/type IV collagen of the basement membrane zone are important factors in cellular migration. Approximately 7–9 days are required to re‐formation of the functional barrier of the skin and normalization of the basement membrane zone.…”

“…The myofibroblast to fibroblast ratio is 1 : 10 from 18 to 40 days 16 and is maintained during the remodelling phase. 10 The wound contracts in proportion to its depth, accounting for up to a 40% decrease in defect size in full‐thickness wounds, which also depends on species and anatomic locations.…”

Sekundäre Wundheilung

“…Dieses trifft nicht nur in Hinblick auf die durch sekundäre Wundheilung erzielten guten funktionellen und ästhetischen Ergebnisse zu, sondern begründet sich durch die Einzeitigkeit des Verfahrens und die geringe postoperative Wundinfektions-wie auch Schmerzinduktionsrate. So bedurfte in unserem Kollektiv kein Patient einer antibiotischen oder analgetischen Therapie, was auch in anderen klinischen Studien belegt wurde [11,13,16,24]. Ein weiterer Vorteil der sekundären Wundheilung besteht in dem geringen Kostenaufwand [13,27], ebenfalls begründet durch die Einzeitigkeit und geringe Komplikationsrate des Verfahrens.…”