Health Benefits and Positive Acute Effects of Psilocybin Consumption: A Quantitative Textual Analysis of User Self-Reported Data

Bienemann, Bheatrix; Barbosa, Amanda Rocha; Cruz, Lucas Villar Magalhães da; Multedo, Marco; Mograbi, Daniel C.

doi:10.1080/02791072.2023.2226414

Cited by 3 publications

(1 citation statement)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another avenue of research would be to explore substances with traditional use that more recently have been incorporated into mainstream treatments. For example, psilocybin has been known to lead to changes in the sense of self, with users typically reporting “ego‐dissolution” (a reduction of self‐reference and a disintegration in the boundaries between the self and the world), in both negative and positive experiences with psilocybin (Bienemann et al, 2020; 2023). Considering the boom in research on psychedelics, investigating self‐awareness may help bringing some of these compounds into clinical practice, also providing resources for a cognitive neuroscience of self‐awareness.…”

Section: Alternative Framework and Future Research Directionsmentioning

confidence: 99%

The cognitive neuroscience of self‐awareness: Current framework, clinical implications, and future research directions

Mograbi,

Hall,

Arantes

et al. 2023

WIRES Cognitive Science

Self Cite

View full text Add to dashboard Cite

Self‐awareness, the ability to take oneself as the object of awareness, has been an enigma for our species, with different answers to this question being provided by religion, philosophy, and, more recently, science. The current review aims to discuss the neurocognitive mechanisms underlying self‐awareness. The multidimensional nature of self‐awareness will be explored, suggesting how it can be thought of as an emergent property observed in different cognitive complexity levels, within a predictive coding approach. A presentation of alterations of self‐awareness in neuropsychiatric conditions will ground a discussion on alternative frameworks to understand this phenomenon, in health and psychopathology, with future research directions being indicated to fill current gaps in the literature.This article is categorized under: Philosophy > Consciousness Psychology > Brain Function and Dysfunction Neuroscience > Cognition

show abstract

Section: Alternative Framework and Future Research Directionsmentioning

confidence: 99%

The cognitive neuroscience of self‐awareness: Current framework, clinical implications, and future research directions

Mograbi,

Hall,

Arantes

et al. 2023

WIRES Cognitive Science

Self Cite

View full text Add to dashboard Cite

show abstract

Brain Networks, Neurotransmitters and Psychedelics: Towards a Neurochemistry of Self-Awareness

Mograbi,

Rodrigues,

Bienemann

et al. 2024

Curr Neurol Neurosci Rep

View full text Add to dashboard Cite

Purpose of Review Self-awareness can be defined as the capacity of becoming the object of one’s own awareness and, increasingly, it has been the target of scientific inquiry. Self-awareness has important clinical implications, and a better understanding of the neurochemical basis of self-awareness may help clarifying causes and developing interventions for different psychopathological conditions. The current article explores the relationship between neurochemistry and self-awareness, with special attention to the effects of psychedelics. Recent Findings The functioning of self-related networks, such as the default-mode network and the salience network, and how these are influenced by different neurotransmitters is discussed. The impact of psychedelics on self-awareness is reviewed in relation to specific processes, such as interoception, body ownership, agency, metacognition, emotional regulation and autobiographical memory, within a framework based on predictive coding. Summary Improved outcomes in emotional regulation and autobiographical memory have been observed in association with the use of psychedelics, suggesting higher-order self-awareness changes, which can be modulated by relaxation of priors and improved coping mechanisms linked to cognitive flexibility. Alterations in bodily self-awareness are less consistent, being potentially impacted by doses employed, differences in acute/long-term effects and the presence of clinical conditions. Future studies investigating the effects of different molecules in rebalancing connectivity between resting-state networks may lead to novel therapeutic approaches and the refinement of existing treatments.

show abstract

Therapeutic Protocols Using Ketamine and Esketamine for Depressive Disorders: A Systematic Review

K. Freind,

Beserra,

Menezes

et al. 2023

Journal of Psychoactive Drugs

View full text Add to dashboard Cite

Health Benefits and Positive Acute Effects of Psilocybin Consumption: A Quantitative Textual Analysis of User Self-Reported Data

Cited by 3 publications

References 32 publications

The cognitive neuroscience of self‐awareness: Current framework, clinical implications, and future research directions

The cognitive neuroscience of self‐awareness: Current framework, clinical implications, and future research directions

Brain Networks, Neurotransmitters and Psychedelics: Towards a Neurochemistry of Self-Awareness

Therapeutic Protocols Using Ketamine and Esketamine for Depressive Disorders: A Systematic Review

Contact Info

Product

Resources

About