Health-related quality of life and prosthesis use among patients amputated due to peripheral arterial disease – a one-year follow-up

Torbjörnsson, Eva; Ottosson, Carin; Boström, Lars; Blomgren, Lena; Malmstedt, Jonas; Fagerdahl, Ann‐Mari

doi:10.1080/09638288.2020.1824025

Cited by 15 publications

(13 citation statements)

References 44 publications

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“… 2 Long-term pain after amputation can have significant negative consequences, including depression, 3 disability, 4 unemployment 5 and poorer health-related quality of life. 6 Opioids are routinely used for pain management following lower limb amputation 7 ; however, only a minority of lower limb amputees in the UK experience ‘good’ acute pain control. 8 The side effects of opioids are well-established, including sedation, 9 nausea and vomiting, 10 constipation 11 and pruritus.…”

Section: Introductionmentioning

confidence: 99%

“…Acute postoperative pain is common among amputees,1 and is associated with chronic residual and phantom limb pain 2. Long-term pain after amputation can have significant negative consequences, including depression,3 disability,4 unemployment5 and poorer health-related quality of life 6. Opioids are routinely used for pain management following lower limb amputation7; however, only a minority of lower limb amputees in the UK experience ‘good’ acute pain control 8.…”

Section: Introductionmentioning

confidence: 99%

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Exploring patients’ experiences of analgesia after major lower limb amputation: a qualitative study

et al. 2021

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ObjectivesTo explore patient experiences, understanding and perceptions of analgesia following major lower limb amputation.DesignQualitative interview study, conducted as part of a randomised controlled feasibility trial.SettingParticipants were recruited from two general hospitals in South Wales.ParticipantsInterview participants were patients enrolled in PLACEMENT (Perineural Local Anaesthetic Catheter aftEr Major lowEr limb amputatioN Trial): a randomised controlled feasibility trial comparing the use of perineural catheter (PNC) versus standard care for postoperative pain relief following major lower limb amputation. PLACEMENT participants who completed 5-day postoperative follow-up, were able and willing to participate in a face-to-face interview, and had consented to be contacted, were eligible to take part in the qualitative study. A total of 20 interviews were conducted with 14 participants: 10 male and 4 female.MethodsSemi-structured, face-to-face interviews were conducted with participants over two time points: (1) up to 1 month and (2) at least 6 months following amputation. Interviews were audio-recorded, transcribed verbatim and analysed using a framework approach.ResultsInterviews revealed unanticipated benefits of PNC usage for postoperative pain relief. Participants valued the localised and continuous nature of this mode of analgesia in comparison to opioids. Concerns about opioid dependence and side effects of pain relief medication were raised by participants in both treatment groups, with some reporting trying to limit their intake of analgesics.ConclusionsFindings suggest routine placement of a PNC following major lower limb amputation could reduce postoperative pain, particularly for patient groups at risk of postoperative delirium. This method of analgesic delivery also has the potential to reduce preoperative anxiety, alleviate the burden of pain management and minimise opioid use. Future research could further examine the comparison between patient-controlled analgesia and continuous analgesia in relation to patient anxiety and satisfaction with pain management.Trial registration numberISRCTN: 85710690; EudraCT: 2016-003544-37.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Exploring patients’ experiences of analgesia after major lower limb amputation: a qualitative study

et al. 2021

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“…A generous prescription of prostheses and rehabilitation after amputation will give the patient a chance to improve his/ her HRQOL 31 . This shall be achieved via institution of individualized postoperative physiotherapy and exercise programmed, easy access to rehabilitation centers and preoperative training of amputee patient for successful rehabilitation after surgery.…”

Section: Discussionmentioning

confidence: 99%

Health Related Quality of Life in patients undergoing Lower Limb Amputation secondary to Peripheral Arterial Disease

Hashim¹,

Zarmina²,

Panhwar³

et al. 2023

PJMHS

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Aim: To assess domains of health-related quality of life among patients undergoing major lower limb amputation secondary to peripheral arterial disease. Study design: Observational questionnaire-based study. Place and Duration: Data from 1st January to 31 December 2020(collected from September 2022 to November 2022) was assessed out of which ninety-one patients fulfilled the inclusion criteria. Methodology: Twenty-three patients were interviewed after verbal consent over telephone using validated questionnaires: World Health Organization Quality of Life-BREF, Amputee Single Item Mobility Measure, Locomotor Capability Index-5. Independent sample t-tests and ANOVA were performed for demographics and domain scores. Pearson-Correlation tests were performed for relations between domains and mobility scores. Results: 12 (52.20%) of interviewed patients received below knee amputation, comprising mostly of males 16 (69.60%) with diabetes 18 (78.30%). Participants who used prosthesis had statistically significantly greater mobility scores compared to non-prosthesis users t(21)=3.396, p=0.03. Below knee amputees report better quality of life compared to above knee as these amputees had lower physical domain (mean difference -22.75, p=0.027) and environmental domain scores (mean difference -12.44, p=0.009). This study found that male participants had statistically significantly greater physical t(21)=2.698, p=0.013 and environmental t(21)=2.77,1 p =0.011 scores after a major lower limb amputation compared to females. Conclusion: Males and patients with prosthesis report significantly better quality of life compared to females and non-prosthesis users, owing to socioeconomic and cultural barriers. Keywords (MeSH): Amputation, Surgical, peripheral arterial disease, Artificial Limbs, Quality of Life

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“…Amputations cause significant alterations in one's everyday functioning and quality of life. Amputation-related limitations on the body's structures and functions have an impact on a person's level of activity and social engagement (4) .…”

Section: Introductionmentioning

confidence: 99%

“…There is a correlation between mobility, use of a prosthesis, and perceived HRQOL among patients with amputation (4,6) . Mobility is one of the most significant variables for excellent HRQOL since low functional status reduces the patient's ability to live independently.…”

Section: Introductionmentioning

confidence: 99%

Health Related Quality of Life for Patients with Diabetic Foot Amputation

Ahmed¹,

Mahmoud²,

Saad³

2023

The Egyptian Journal of Hospital Medicine

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Background: In the latter stages of many illnesses, such as diabetes mellitus, limb amputation is a life-altering treatment that has social, psychological, and functional repercussions that lower the patient's quality of life. Objective: The current study aimed to assess the health-related quality of life for patients with diabetic foot amputation. Patients and methods: A descriptive exploratory study was conducted at the Outpatient Clinic affiliated to Beni-Suef University Hospital. A total of 70 diabetic patients, 3 to 18 after amputation operation for follow up, were recruited using a purposive sample. Data of participants were collected using two tools; (I): Structured interviewing questionnaire, it included three parts; socio-demographic characteristics of patients, medical history of patients and knowledge assessment questionnaire. (II) World Health Organization quality of life SF36 questionnaire. Results: About 51.4% of studied patients were in the age group 50 -<60 years, 58.6% of them had unsatisfactory total knowledge level regarding diabetic foot and amputation, and 60% of them had unhealthy or poor quality of life. There was no statistically significant correlation between total knowledge and total quality of life regarding diabetic foot amputation. Conclusion: Developing and implementing an educational programme for patients with diabetic foot amputation for improvement of their quality of life is strongly and urgently needed.

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Health-related quality of life and prosthesis use among patients amputated due to peripheral arterial disease – a one-year follow-up

Abstract: Fagerdahl (2020): Health-related quality of life and prosthesis use among patients amputated due to peripheral arterial disease-a one-year follow-up, Disability and Rehabilitation,

Cited by 15 publications

References 44 publications

Exploring patients’ experiences of analgesia after major lower limb amputation: a qualitative study

Exploring patients’ experiences of analgesia after major lower limb amputation: a qualitative study

Health Related Quality of Life in patients undergoing Lower Limb Amputation secondary to Peripheral Arterial Disease

Health Related Quality of Life for Patients with Diabetic Foot Amputation

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