Health‐Related Quality of Life and Its Contributory Factors in Allergic Rhinitis Patients in Nigeria

Adebola, Stephen Oluwatosin; Abidoye, Babatunde O.; Ologe, Foluwasayo E.; Adebola, Oyebola Eyitayo; Oyejola, B. A.

doi:10.1177/0194599814541627a285

Cited by 2 publications

(2 citation statements)

References 18 publications

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“…We used a 6-parameter symptom score for CRS patients and controls to evaluate severity of symptoms correlated to anti-staphylococcal IgG levels. A similar symptom score has been used in a previous study (36) . Not surprisingly, the patients had a significantly higher…”

Section: Holm-bonferroni Correction For Multiple Comparison Wasmentioning

confidence: 99%

Anti-Staphylococcal humoral immune response in patients with chronic rhinosinusitis

Thunberg¹,

Hugosson²,

Fredlund³

et al. 2019

RHINOL

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Background: Staphylococcus aureus (S. aureus) can behave both as a harmless commensal and as a pathogen. Its significance in the pathogenesis of chronic rhinosinusitis (CRS) is not yet fully understood. This study aimed to determine serum antibody responses to specific staphylococcal antigens in patients with CRS and healthy controls, and to investigate the correlation between specific antibody response and severity of symptoms. Methodology: Serum samples from 39 patients with CRS and 56 healthy controls were analysed using a protein microarray to investigate the antibody response to S. aureus specific antigens, with a focus on immunoglobulin G (IgG) directed toward staphylococcal components accessible to the immune system. Holm-Bonferroni corrections were applied in all analyses. Information about growth of S. aureus in nares and maxillary sinus was taken from a previous study based on the same individuals. Clinical symptoms were assessed using a scoring system. Results: IgG antibody levels toward staphylococcal TSST-1 and LukF-PV were significantly higher in the CRS patient group compared to healthy controls, and levels of anti-TSST-1 antibodies were significantly higher in the CRS patient group with S. aureus in maxillary sinus than in controls. There were no correlations between the severity of symptoms and levels of serum anti-staphylococcal IgG antibody levels for LukF-PV and TSST-1. Conclusions: TSST-1 and LukF-PV could be interesting markers for future studies of the pathogenesis of CRS.

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Section: Holm-bonferroni Correction For Multiple Comparison Wasmentioning

confidence: 99%

Anti-Staphylococcal humoral immune response in patients with chronic rhinosinusitis

Thunberg¹,

Hugosson²,

Fredlund³

et al. 2019

RHINOL

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show abstract

“…[15][16][17] Only a few studies concerning this topic have been carried out at the community level on this continent. These include studies that examined the HRQoL among allergic rhinitis patients 18 , patients with tuberculosis 19 , adolescents living with sickle cell disease, 20 , and oral HRQoL of school teachers. 21 However, none of these studies investigated the impact of specific illnesses on the HRQoL of older people in Nigeria.…”

Section: Introductionmentioning

confidence: 99%

Associations of chronic illnesses and socio-demographic factors with health-related quality of life of older adults in Nigeria: A cross-sectional study

Faronbi

Ajadi

Gobbens³

2020

gmj

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Background: The increase in life expectancy has brought about a higher prevalence of chronic illnesses among older people.Objectives: To identify common chronic illnesses among older adults, to examine the influence of such conditions on their Health-Related Quality of Life (HRQoL), and to determine factors predicting their HRQoL.Method: A population-based cross-sectional study was conducted involving 377 individuals aged 60 years and above who were selected using multi-stage sampling techniques in Olorunda Local Government, Osun State, Nigeria. Data were collected using an interviewer-administered questionnaire comprising socio-demographic characteristics, chronic illnesses, and the World Health Organization quality of life instrument (WHOQOL-BREF) containing physical health, psychological, social relationships, and environmental domains.Results: About half (51.5%) of the respondents reported at least one chronic illness which has lasted for 1–5 years (43.3%). The prevalence of hypertension was 36.1%, diabetes 13.9% and arthritis 13.4%. Respondents with chronic illness had significantly lower HRQoL overall and in the physical health, social relationships and the environmental domains (all p<0.05) compared to those without a chronic illness. Factors that predicted HRQoL include age, marital status, level of education, the presence of chronic illness and prognosis of the condition.Conclusion: This study concluded that chronic illness is prevalent in Nigerian older people and significantly influence their HRQoL. Age, marital status, and level of education were associated with HRQoL in this group.Keywords: Chronic illness, Health-Related Quality of Life, Older adults, Socio-demographic factorsFunding: Postdoctoral fellowship from Consortium for Advanced Research Training in Afric

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Health‐Related Quality of Life and Its Contributory Factors in Allergic Rhinitis Patients in Nigeria

Cited by 2 publications

References 18 publications

Anti-Staphylococcal humoral immune response in patients with chronic rhinosinusitis

Anti-Staphylococcal humoral immune response in patients with chronic rhinosinusitis

Associations of chronic illnesses and socio-demographic factors with health-related quality of life of older adults in Nigeria: A cross-sectional study

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