Health-related quality of life as a predictor of mortality in heterogeneous samples of older adults

Liira, Helena; Mavaddat, Nahal; Eineluoto, Maija; Kautiainen, Hannu; Strandberg, Timo; Suominen, Merja; Laakkonen, Marja‐Liisa; Eloniemi‐Sulkava, Ulla; Sintonen, Harri; Pitkälä, Kaisu H.

doi:10.1007/s41999-018-0029-3

Cited by 15 publications

(31 citation statements)

References 33 publications

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“…Our ndings are in line with a previous study that used pooled analysis [29] of eight heterogenous Finnish cohorts using the 15D HRQoL measure and included a wide range of both community-dwelling participants with or without morbidity, such as cardiovascular disease, dementia, and hospitalized patients with delirium. They also found that the 15D HRQoL measure was associated with two-year survival, with a slightly higher hazard ratio than that found in our study (HR per 1-SD = 0.44, 95% CI 0.40 to 0.48) [29]. These differences may relate to their inclusion of patient groups in generally poorer health, while our systematic review focused on the community dwelling population.…”

Section: Discussionsupporting

confidence: 90%

“…Two published articles of De Buyser et al reported the results of the same populationbased cohort study [41,42], three published articles by De Salvo et al and Fan et al were from the same study and included participants enrolled in the Veterans Affairs Ambulatory Care Quality Improvement Project [24,43,47], two published studies of Mold et al and Lawler et al used the same communitydwelling cohort [57,61], two published studies of Higueras-Fresnillo et al and Otero-Rodriguez et al were from the same Spanish cohort [52,67], two published studies of Feeny et al and Kaplan et al were from the same Canadian cohort [48,55]; and Myint et al published three articles [26,64,65] with different perspectives on the same population-based study. Additionally, Liira et al's study [29], included eight individual cohorts, however, only ve of the cohorts met the inclusion criteria for this current systematic review, and thus are shown in Table 1.…”

Section: Description Of Included Studiesmentioning

confidence: 99%

“…Five Finnish individual cohorts of the Liira et al study including 2,377 [29] measured QoL using the 15D index and explored its association with all-cause mortality using time-to-event survival analysis. With an average 2-year follow-up, one SD (0.14) increase in the 15D index was associated with a 36.7% decrease in all-cause mortality (pooled HR = 0.633; 95%CI: 0.514 to 0.780; P-value < 0.001).…”

Section: Meta-analysesmentioning

confidence: 99%

“…low for the purpose of consistency across the table [38,44] Six Dimensions Short Form Scale SF-6D Study [26,53] Euro Quality of Life scale EQ-5D Study [39,53] Health Utilities Index 3 HUI3 Study [48,55] Psychological General Well-Being Index PGWB Study [66] 15-dimensional index 15D Study [29] Goteborg Quality of Life Instrument Goteborg QoL Study [73] Lancashire *where studies report reverse association or risk estimate per more than 1-unit increase, the risk estimates were standardised per 1-unit increase or 1-SD increase or high vs. low for the purpose of consistency across the table…”

Section: Competing Interestsmentioning

confidence: 99%

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Quality of Life and mortality in the general population: a systematic review and meta-analysis

Phyo

Freak‐Poli

Craig

et al. 2020

Preprint

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Background: Quality of life (QoL) is multi-dimensional concept of an individual’ general well-being status in relation to their value, environment, cultural and social context in which they live. This study aimed to quantitatively synthesise available evidence on the association between QoL and mortality in the general population.Methods: An electronic search was conducted using three bibliographic databases, MEDLINE, EMBASE and PsycINFO. Inclusion criteria were studies that assessed QoL using standardized tools and examined mortality risk in a non-patient population. Qualitative data synthesis and meta-analyses using a random-effects model were performed.Results: Of 4,184 articles identified, 47 were eligible for inclusion, involving approximately 1,200,000 participants. Studies were highly heterogeneous in terms of QoL measures, population characteristics and data analysis. In total, 43 studies (91.5%) reported that better QoL was associated with lower mortality risk. The results of four meta-analyses indicated that higher health-related QoL (HRQoL) is associated with lower mortality risk, which was consistent for overall HRQoL (HR 0.633, 95% CI: 0.514 to 0.780), physical function (HR 0.987, 95% CI: 0.982 to 0.992), physical component score (OR 0.950, 95% CI: 0.935 to 0.965), and mental component score (OR 0.980, 95% CI: 0.969 to 0.992).Conclusion: These findings provide evidence that better QoL/HRQoL was associated with lower mortality risk. The utility of these measures in predicting mortality risk indicates that they should be considered further as potential screening tools in general clinical practice, beyond the traditional objective measures such as body mass index and the results of laboratory tests.

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Section: Discussionsupporting

confidence: 90%

Section: Description Of Included Studiesmentioning

confidence: 99%

Section: Meta-analysesmentioning

confidence: 99%

Section: Competing Interestsmentioning

confidence: 99%

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Quality of Life and mortality in the general population: a systematic review and meta-analysis

Phyo

Freak‐Poli

Craig

et al. 2020

Preprint

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“…Declining functional levels in older adults may be directly or indirectly related to their quality of life, major health problems, and mortality. 26,27) Assessment of the independence level of functions helps healthcare personnel to provide appropriate treatment, care, and counseling services by identifying the needs of older individuals and taking necessary measures. 28) This study adapted the Lawton-IADL, which is used to determine the IADL level in older adults, and analyzed its validity and reliability.…”

Section: Discussionmentioning

confidence: 99%

Adaptation of the Lawton Instrumental Activities of Daily Living Scale to Turkish: Validity and Reliability Study

Işık

Yilmaz

Uysal

et al. 2020

Ann Geriatr Med Res

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Functional capacity is a complex concept that includes basic activities of daily living (BADL), instrumental activities of daily living (IADL), 1) and advanced activities. 2) Since inadequacies in BADL affect daily activities, work performance, and leisure activities, BADL is one of the most important indicators of success to define the skill level, demonstrate the effectiveness of rehabilitation, and determine a person's ability to perform activities of daily living. 3,4) The BADL may decline due to age, a specific disease, or a variety of factors such as decreased muscle strength, muscle atrophy, degenerative changes in joints, impaired neuromuscular coordination, loss of vision, and postural changes. 5) BADL represent the activities necessary for self-care (e.g., bathing, dressing, feeding, etc.) while IADL represent the activities that allow independence in social life. 6,7) In addition to some BADL, Background: The Lawton Instrumental Activities of Daily Living (IADL) scale is the most widely used scale for the assessment of IADL in the elderly population. The aim of this study was to adapt the Lawton IADL Scale in Turkish and to investigate the validity and the reliability of the scale in older adults. Methods: A total of 80 participants with a mean age of 71.6±5.8 years were included in the study. The independent living skills of the older adults were measured using Lawton IADL, Hodkinson Mental Test, Functional Independence Scale, Barthel Index, Katz Index, and visual analog scale. Lawton IADL was translated into Turkish, validated by professional reviewers, translated back into English, and then tested. Cronbach's alpha was used to measure reliability in a group of 34 participants and test-retest was performed 1 week after the first test. Pearson correlation analysis was used to show the relationship between Lawton IADL and other scales and indexes. Results: Internal consistency (Cronbach's alpha) value was 0.843 for the whole scale. The intraclass correlation coefficient value of the scale was 0.915. Conclusion: These results confirm that the Turkish version of the Lawton IADL scale has excellent reliability and validity.

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Self‐efficacy, resilience and healthy ageing among older people who have an acute hospital admission: A cross‐sectional study

Remm,

Halcomb,

Peters

et al. 2023

Nursing Open

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AimTo examine the associations between self‐efficacy, resilience and healthy ageing among older people who have an acute hospital admission.DesignA cross‐sectional study.MethodsSurvey and medical record data were collected from older people on discharge from hospital. The survey measured self‐efficacy with the 6‐item General Self‐Efficacy scale (GSE‐6), resilience with the Brief Resilience Scale (BRS), and healthy ageing with the Selfie Ageing Index (SAI). Medical record data included potential confounders: co‐morbidities, frailty items, previous falls and previous admission in the last 28 days. Multi‐linear regression and Spearman's rank correlation coefficient were used to examine the independent associations between self‐efficacy, resilience and healthy ageing.ResultsResponses were received from 143 older people (mean age 79). After adjusting for potential confounders, co‐morbidities (ß = ‐0.08, p = 0.001) remained negatively associated with healthy ageing, while self‐efficacy (ß = 0.03, p = 0.005) and resilience (ß = 0.05, p < 0.001) remained positively associated with healthy ageing (R2 = 0.243). Positive correlations were found between self‐efficacy (ρ = 0.33, p < 0.01), resilience (ρ = 0.38, p < 0.001) and healthy ageing. Positive correlations were also found between self‐efficacy and resilience (ρ = 0.38, p < 0.01). Those with lower self‐efficacy and resilience were more likely to report reduced activities of daily living, mobility, physical activity and mood.ConclusionFindings indicate that while the number of co‐morbidities have negative consequences for healthy ageing among older people who are hospitalised, the promotion of self‐efficacy and resilience can potentially contribute to healthy ageing within the physical and psychological domains.Implications for Patient CareNurses can promote self‐efficacy, which can potentially increase resilience and help to improve self‐management of chronic conditions, functional ability in daily activities, mobility and physical activity and reduce both anxiety and depressive symptoms.Patient ContributionParticipant feedback throughout the data collection process assisted in the evaluation of study methods and data interpretation. This included processes such as assessing selected tools and clarifying the meanings of healthy ageing factors.

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Health-related quality of life as a predictor of mortality in heterogeneous samples of older adults

Cited by 15 publications

References 33 publications

Quality of Life and mortality in the general population: a systematic review and meta-analysis

Quality of Life and mortality in the general population: a systematic review and meta-analysis

Adaptation of the Lawton Instrumental Activities of Daily Living Scale to Turkish: Validity and Reliability Study

Self‐efficacy, resilience and healthy ageing among older people who have an acute hospital admission: A cross‐sectional study

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