Health-related quality of life associated with irritable bowel syndrome: Comparison with other chronic diseases

Quality of Life in Autosomal Dominant Polycystic Kidney Disease Patients not yet on Dialysis

“…only factors consistently shown to relate to MCS scores include age, socioeconomic status, and mental illness (12,20,21). Importantly, this study supports the original observations made in other chronic kidney disease populations that the SF-36 questionnaire does not provide the sensitivity necessary to detect clinically relevant dissatisfaction with quality of life and, specifically to ADPKD, is inadequate to detect changes that relate to increasing cystic burden with age.…”

Management of Irritable Bowel Syndrome

“…Finally, a therapeutic response in IBS-related symptoms corresponds to an improvement in HRQOL. The scores of patients in IBS reference groups were significantly lower on several SF-36 domains than those of the US normative population (20). Scores on several SF-36 scales were also significantly lower in the IBS reference groups compared with the GERD, asthma, and migraine samples.…”

Chronic Abdominal Pain in Children

“…Quality of life in adult patients with chronic abdominal pain is substantially poorer than that of the general population. 3 The economic cost related to this condition in children is not known but is likely to be substantial, considering that expenses associated with irritable bowel syndrome (IBS) in adults have been estimated to be $8 billion to $30 billion per year. [4][5][6] The long-term outcome of this condition has not been determined, but preliminary data indicate that young adults with a history of recurrent abdominal pain that began in childhood who are treated by a subspecialist are significantly more likely than their peers without recurrent abdominal pain to have lifelong psychiatric problems and migraine headaches.…”