Health-related quality of life in Romanian postmenopausal women with osteoporosis and fragility fractures

Ciubean, Alina Deniza; Ungur, Rodica; Irsay, László; Ciortea, Viorela Mihaela; Borda, Ileana Monica; Onac, Ioan; Vesa, Ștefan Cristian; Buzoianu, Anca Dana

doi:10.2147/cia.s190440

Cited by 37 publications

(31 citation statements)

References 36 publications

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“…On the other hand, it should be noted that regardless of the presence of bone fractures, women with osteoporosis show a reduced quality of life in different QUALEFFO-41 domains. This is con rmed by reports of, among others Hopman et al (2019) [24], Ciubean et al [25] and Bianch et. al [26].…”

Section: Discussionsupporting

confidence: 73%

Quality of Life in Women With Postmenopausal Osteoporosis - Pilot Studies in The Łódź Province

Górczewska¹,

Jakubowska-Pietkiewicz²

2020

Preprint

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Osteoporosis is a social disease and epidemic of the 21st century, and is also a growing problem in the ageing Polish society. The aim of the study was to assess the quality of life (QoL) in women with postmenopausal osteoporosis. Material and methods The study was an outpatient, questionnaire-based poll, carried out from VI.2018 to V.2019. A group of 198 women, aged 72.31±8.59 years with diagnosed postmenopausal osteoporosis in two Osteoporosis Clinics in the city of Łódź (Poland) were included. The paper uses: the Polish version of the QUALEFFO 41 quality of life scale, the VAS scale and a survey of my own authorship. The data were analysed using multiple linear regression.Results The average result of QUALEFFO-41 was 40.26±16.92 points. Analysing individual QUALEFFO-41 domains the lowest quality of life was found in the mental function domain (mental function 48.49±18.06 points). The visual analogue scale of pain was 4.87±2.39 points. The VAS scale positively correlated with all QUALEFFO 41 domains. Marital status, education and financial situation had a significant statistical impact on the quality of life (p<;0.05). Multiple regression step-by-step analysis showed that pain expressed on the VAS scale, pain awakening from sleep, taking sleeping pills and older age of respondents deteriorate the quality of life.Conclusion The analysis showed that Polish women with postmenopausal osteoporosis have an average quality of life. In Poland the assessment of quality of life of chronically ill patients and routine evaluation of pain severity on the VAS scale is not common.

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Section: Discussionsupporting

confidence: 73%

Quality of Life in Women With Postmenopausal Osteoporosis - Pilot Studies in The Łódź Province

Górczewska¹,

Jakubowska-Pietkiewicz²

2020

Preprint

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“…Osteoporosis (OP) is a common skeletal disorder characterized by reduced bone mass and disruption of bone microarchitecture, resulting in increased bone fragility and a high fracture risk (1). The patient population suffering from OP and osteopenia is increasing annually worldwide, as is the incidence of osteoporotic fractures.…”

Section: Introductionmentioning

confidence: 99%

Comparison of different calcium supplementation methods in patients with osteoporosis

et al. 2019

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The aim of the present study was to explore the clinical efficacy and safety of different methods of calcium supplementation in osteoporosis (OP). Patients with OP were divided into four groups, including the control, oral calcium supplementation, intravenous calcium supplementation and combined calcium supplementation groups. The duration of the calcium supplementation was 3-6 years. Medical records were collected and examined along with demographic data, the incidence of certain diseases and adverse reactions. All subjects in the three treatment groups exhibited statistically significant reductions in alkaline phosphatase (ALP) levels, visual analog score (VAS) and Oswestry Disability Index (ODI) compared with the respective pre-treatment values. Furthermore, compared with prior to treatment, the lumbar and hip bone mineral density (BMD) of patients receiving intravenous calcium supplementation was significantly increased. In addition, after treatment, the lumbar and hip BMD was significantly increased, whereas ALP levels, VAS and ODI were significantly decreased in the oral calcium supplementation group compared with the control group. Also, compared with the control and oral calcium supplementation groups, the BMD was significantly increased, whereas ALP, VAS, ODI, the rate of infection and tooth loss, the incidence of fragility fractures, joint replacement surgery, arrhythmia, lumbar disc herniation and cerebral infarction were significantly decreased in the two groups treated with intravenous calcium supplementation. The results of the present study may enable a better understanding of the effectiveness and safety of the different methods for supplementing calcium in OP.

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“…This is con rmed by reports of, among others Hopman et al (2019) [24], Ciubean et al [25] and Bianch et. al [26]. This may be related to increased chest kyphosis, decreased lean muscle mass and generalized muscle weakness in these patients [27].…”

Section: Discussionmentioning

confidence: 94%

Quality of Life in Women With Postmenopausal Osteoporosis - Pilot Studies in the Łódź Province

Górczewska

Jakubowska-Pietkiewicz²

2020

Preprint

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BackgroundOsteoporosis is a social disease and epidemic of the 21st century, and is also a growing problem in the ageing Polish society. The aim of the study was to assess the quality of life (QoL) in women with postmenopausal osteoporosis. MethodsThe study was an outpatient, questionnaire-based poll, carried out from VI.2018 to V.2019. A group of 198 women, aged 72.31±8.59 years with diagnosed postmenopausal osteoporosis in two Osteoporosis Clinics in the city of Łódź (Poland) were included. The paper uses: the Polish version of the QUALEFFO 41 quality of life scale, the VAS scale and a survey of my own authorship. The data were analysed using multiple linear regression.ResultsThe average result of QUALEFFO-41 was 40.26±16.92 points. Analysing individual QUALEFFO-41 domains the lowest quality of life was found in the mental function domain (mental function 48.49±18.06 points). The visual analogue scale of pain was 4.87±2.39 points. The VAS scale positively correlated with all QUALEFFO 41 domains. Marital status, education and financial situation had a significant statistical impact on the quality of life (p<;0.05). Multiple regression step-by-step analysis showed that pain expressed on the VAS scale, pain awakening from sleep, taking sleeping pills and older age of respondents deteriorate the quality of life.ConclusionThe analysis showed that Polish women with postmenopausal osteoporosis have an average quality of life. In Poland the assessment of quality of life of chronically ill patients and routine evaluation of pain severity on the VAS scale is not common.

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Health-related quality of life in Romanian postmenopausal women with osteoporosis and fragility fractures

Cited by 37 publications

References 36 publications

Quality of Life in Women With Postmenopausal Osteoporosis - Pilot Studies in The Łódź Province

Quality of Life in Women With Postmenopausal Osteoporosis - Pilot Studies in The Łódź Province

Comparison of different calcium supplementation methods in patients with osteoporosis

Quality of Life in Women With Postmenopausal Osteoporosis - Pilot Studies in the Łódź Province

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