“…15 Therefore, Wu et al 8 used the hearing result at the high frequency of 4.0 kHz for representing the material efficacy for autologous ossiculoplasty and described that 90% of the patients using autografts had closure of the ABG within 20 dB, with a similar effect of titanium, especially in terms of high-frequency improvements at 2-year follow-up. 8 Even more, Sterrer and Loader 16 retrospectively analyzed large sample sizes of 115 patients with COM or cholesteatoma receiving incus interposition graft (N = 62) or PORP (N = 53), and demonstrated incus autograft may have better outcomes than PORP in specific frequencies of 0.25, 1.0, 2.0, and 3.0 kHz. In our study, both the autologous incus and titanium prosthesis groups showed significant hearing benefits in terms of the AC and ABG at 4.0 kHz and the 4-frequency averages, indicating that the material efficacy was similar in the 2 groups.…”