Heart disease and pregnancy: State of the art

Guimarães, Tatiana; Magalhães, Andreia; Veiga, Arminda; Fiúza, Manuela; Ávila, Walkíria Samuel; Pinto, Fausto J.

doi:10.1016/j.repce.2019.06.002

Cited by 8 publications

(7 citation statements)

References 62 publications

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“…Therefore, it can be speculated that the cause for this difference might come from two aspects. Primarily, pregnancy increases the organ burden of patients with a hantavirus infection, worsens the health, and increases the risk of death (Guimarães et al 2019 ). Additionally, the flow dynamics of patients might change during pregnancy.…”

Section: Discussionmentioning

confidence: 99%

Hantavirus Infection during Pregnancy

Jiang

Lian

2020

Virol. Sin.

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Hantavirus infection is a global health challenge, causing widespread public concern. In recent years, cases of hantavirus infection in pregnant women have been reported in many countries. The infected pregnant women and their fetuses appear to have more severe clinical symptoms and worse clinical outcomes. Hence, to study the prevalence of hantavirus infection in pregnant women, this study will focus on the epidemiological distribution of the virus, different virus species penetrating the placental barrier, and factors affecting the incidence and clinical outcome of the infection in pregnant women and their fetuses. In addition, this review will also discuss the diagnostic tools and treatments for pregnant patients and provide an overview of the relevant future research.

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Section: Discussionmentioning

confidence: 99%

Hantavirus Infection during Pregnancy

Jiang

Lian

2020

Virol. Sin.

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“…Esto, contrario a lo observado en nuestra cohorte de pacientes con 3.7% de valoración preconcepcional y mayores tasas de ingreso tardío (73.5%) (CARPREG II 34.5%), resalta la validez de estas escalas para evaluar incluso este grupo de gestantes y la participación del tercer eslabón de prevención, basado en el manejo por un grupo multidisciplinario. Las menores tasas de eventos cardiacos en nuestra cohorte de estudio muestran, en parte, la importancia e impacto significativo que tiene el acceso a la atención por grupos de experiencia, que evalúen y aborden los riesgos en los diferentes aspectos de la salud materno fetal 1,24 . Se estima que aproximadamente la mitad de los desenlaces cardiacos importantes son prevenibles, y una de las estrategias más ampliamente descritas es el acompañamiento por un equipo cardioobstétrico.…”

Section: Discussionunclassified

Validación de los modelos de predicción de desenlaces cardiacos adversos CARPREG II (Cardiac Disease in Pregnancy) y clasificación modificada de la Organización Mundial de la Salud (OMS) en gestantes con cardiopatía

Botero-Builes¹,

Sénior²,

Velásquez-Penagos³

et al. 2022

RCCAR

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Introducción: En gestantes con cardiopatía, los modelos de estratificación del riesgo de desenlaces adversos permiten guiar las decisiones clínicas y establecer estrategias de seguimiento y manejo de acuerdo con cada categoría. Objetivo: Validar los modelos de predicción de riesgo de desenlaces cardiacos adversos CARPREG II y OMSm en gestantes con cardiopatía. Materiales y método: Estudio de validación y comparación de dos modelos de predicción de riesgo en una cohorte prospectiva de gestantes con cardiopatía, valoradas por un equipo cardioobstétrico en un país de ingresos medios. Se evaluaron los desenlaces cardiovasculares y perinatales y se determinó la calibración y el nivel de discriminación de estas herramientas. Resultados: Entre 328 gestantes (27 años DE = 7), el 33% (n = 110) tenían cardiopatía congénita, el 30% (n = 98) arritmias, el 14% (n = 46) valvulopatías y el 9% (n = 29) miocardiopatía. Un evento cardiaco ocurrió en el 15% (10% primario y 5% secundario). La discriminación de ambos modelos fue adecuada (AUC-ROC: 0.74; IC 95%: 0.64-0.84 para CARPREG II y 0.77 para OMSm; IC 95%: 0.69-0.86). La calibración también es buena . Las variables numéricas fracción de eyección y presión sistólica de la arteria pulmonar, pueden mejorar la capacidad de predicción del CARPREG II. Conclusiones: Los modelos CARPREG II y OMSm tienen buena capacidad de predicción del riesgo de desenlaces cardiacos adversos y se ajustan a nuestras gestantes con cardiopatía.

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“…The principal management depends on the severity of MS; if moderate stenosis (valve area 1.0–1.5 cm 2 ) was detected, then either regular close monitoring or intervention is required. In the case of asymptomatic and severe mitral stenosis (valve area < 1.0 cm 2 ), the best method is elective percutaneous balloon valvuloplasty performed during the midtrimester or 20 weeks earlier of gestation [ 26 ]. However, open-heart surgery is ready for maternal life-threatening conditions.…”

Section: Cardiac Events and Stroke In Pregnancymentioning

confidence: 99%

Role of MicroRNAs in Cardiac Disease with Stroke in Pregnancy

Salma

Alshaikh

Alanazi

et al. 2022

Oxidative Medicine and Cellular Longevity

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Pregnancy-related cardiovascular disease with stroke remains a considerable source of higher maternal morbidity and mortality occurs in periods of pregnancy, delivery, and postpartum. It is essential to counsel the mother before pregnancy by an expert cardiologist and obstetric team to discuss any event related to preexistent cardiac or past preeclampsia for estimation of maternal and fetal risks. In pregnancy, the cardiac state includes hypertensive disorders, ischemic heart disease, valvular disease, and postpartum stroke. The incidence of stroke is increasing in pregnancy, particularly in postpartum, and its strong relationship with hypertensive disorders of pregnancy (preeclampsia). The combined cardiologist and obstetrics team requires during pregnancy mainly due to the approach to the management of a cardiac disease that subsequently prevents stroke postpartum. Therefore, a general perception of cardiac disease during pregnancy, delivery, and postpartum should be a core knowledge extent for all cardiovascular and clinicians. Many studies provided linked that deregulation of microRNAs (miRNAs) in maternal circulation and placenta tissue may development of pregnancy complications including preeclampsia considered a diagnostic marker. The desire of this review provides a detailed outline of current knowledge and dealing in this field with strength on the physiological changes during pregnancy.

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Heart disease and pregnancy: State of the art

Cited by 8 publications

References 62 publications

Hantavirus Infection during Pregnancy

Hantavirus Infection during Pregnancy

Validación de los modelos de predicción de desenlaces cardiacos adversos CARPREG II (Cardiac Disease in Pregnancy) y clasificación modificada de la Organización Mundial de la Salud (OMS) en gestantes con cardiopatía

Role of MicroRNAs in Cardiac Disease with Stroke in Pregnancy

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