Heart rate variability in adolescents with functional hypothalamic amenorrhea and anorexia nervosa

Maintenance of parasympathetic inhibition following emotional induction in patients with restrictive type anorexia nervosa

“…A literature review (Mazurak et al, 2011) reported a parasympathetic hyperactivity generally observed in patients suffering from AN at rest or during a 24-h recording. Specifically, despite methodological differences, research generally supports the notion of tonic (at rest) parasympathetic hyperactivity in patients suffering from ED and starvation (Petretta et al, 1997;Galetta et al, 2003;Green et al, 2009;Vögele et al, 2009;Jacoangeli et al, 2013;Bomba et al, 2014). The parasympathetic hyperactivity reported in these patients does not support the observations of Thayer et al, whereby a tonic parasympathetic activity reported best abilities in emotion regulation.…”

Paradoxical increase of plasma vitamin B12 and folates with disease severity in anorexia nervosa

“…Anorexia nervosa (AN) is a common eating disorder (ED) which presents as a complex psychiatric condition associated with severe loss of weight and excessive concern about body weight and shape with, sometime, weight‐regulatory behaviors. The prevalence in young females is relatively high, with a peak of incidence in adolescence, and is especially alarming given the associated considerable mortality rate, and other medical complications , . Moreover, refeeding syndrome poses additional risk to AN patients as a relevant metabolic disturbance to nutritional rehabilitation , .…”

“…The prevalence in young females is relatively high, 1 with a peak of incidence in adolescence, and is especially alarming given the associated considerable mortality rate, 2 and other medical complications. 3,4 Moreover, refeeding syndrome poses additional risk to AN patients as a relevant metabolic disturbance to nutritional rehabilitation. 5,6 In particular, refeeding-associated liver steatosis with increased expression of associated markers is a problem often encountered in clinical practice.…”

Moving beyond self‐report data collection in the natural environment: A review of the past and future directions for ambulatory assessment in eating disorders

“…frequency (e.g., low frequency, high frequency, power) domains were reported (Task Force, 1996). Similar to the broader heart rate variability literature in anorexia nervosa and bulimia nervosa (Mazurak et al, 2011;Peschel et al, 2016), ambulatory heart rate variability assessments in naturalistic settings yielded inconsistent findings; two studies documented higher heart rate variability parameters in anorexia nervosa (Bomba et al, 2014;Galetta et al, 2003), though one study indicated reduced sympathetic activity in anorexia nervosa and bulimia nervosa samples (Melanson et al, 2004). One study demonstrated that heart rate variability normalized after weight restoration in anorexia nervosa (Mont et al, 2003).…”